Abstract: Goat milk powder is the main goat milk product in China. However,the explorations of its function and added value are lack of evidences. In order to evaluate the effects of goat milk powder on the enhancing physical vitality,160 male BALB/c mice aged 5 to 6 weeks were randomly divided into four groups,which were control,positive control,low dose and high dose of goat milk powder. The control group of mice were administered intragastrically with 200 μL of normal saline,and the positive control of mice were administered intragastrically with 625.0 mg/kg of American ginseng tablet,and low dose and high dose of goat milk powder groups were respectively intragastrically with 6.25 g/kg and 12.5 g/kg of goat milk powder per day. After 30-day gavage,the swimming times under burden of mice were measured,and the concentrations of lactic acid in blood,serum urea and the hepatic glycogen were detected. The results suggested that the swimming under burden time of goat milk powder groups was significantly longer than that in the control group（p< 0.05）.Compared to control group,the level of serum urea of goat milk powder groups was significantly reduced,and the hepatic glycogen content was significantly increased（p< 0.05）. The areas under curve of blood lactic acid had no significant difference in these groups. The results of this study suggested that goat milk powder could enhance physical vitality.

Key words: goat milk powder, physical vitality, urea, hepatic glycogen, blood lactic acid