China Dairy ›› 2026, Vol. 0 ›› Issue (5): 111-119.doi: 10.12377/1671-4393.26.05.16

• DAIRY INDUSTRY • Previous Articles     Next Articles

Advances in Research on the Impacts of Milk Fat Globule Membrane on Human Health

KOU Chunyu, SHI Yang, WANG Shuai, NIAN Jingqi, CHE Jialing   

  1. Beidahuang Wondersun Dairy Company Limited,Harbin Heilongjiang 150036
  • Online:2026-05-25 Published:2026-06-18

Abstract: Milk Fat Globule Membrane(MFGM)is a naturally occurring protective membrane structure present in both human and bovine milk,which maintains the stability of milk emulsions by inhibiting fat aggregation and oxidation. The core components of MFGM are composed of a diverse array of polar lipids and functional proteins. Its specific composition is modulated by both endogenous physiological factors(including the dietary composition,breed,and health status of dairy cows)and exogenous production and processing factors,resulting in significant compositional heterogeneity among MFGM preparations from different sources. In recent years,with in-depth research on the physiological functions of MFGM and its benefits to human health,especially the gradual elucidation of its health-promoting effects on early-life brain development,cognitive function,skeletal muscle and cardiac metabolism,MFGM has emerged as a prominent research hotspot in the field of nutrition and food science. This review provided an in-depth discussion of the nutritional and functional properties of MFGM,highlighted the latest supporting clinical evidence,and offered an outlook on the development prospects and future application directions of MFGM as a core functional ingredient in functional foods.

Key words: milk fat globule membrane(MFGM), human health, physiological functions, structure, separation and purification

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