Bovine tuberculosis is a zoonotic chronic infectious disease caused by Mycobacterium bovine tuberculosis infection.It can be infected by cattle,sheep, pigs and humans,and dairy cows are the most susceptible.Sick livestock and patients are the main source of infection of the disease.The disease can be spread through bacteria-carrying sputum, milk, and contaminated feed.The routes of infection include the respiratory tract and digestive tract.There is no obvious seasonality in the disease.The clinical manifestation is cough, Low fever,weight loss in the middle and late stages,affecting economic benefits and threatening the health of livestock and humans.