Chloropropanol esters and glycidyl esters are the processing contaminants formed during the refining of edible oils.Chloropropanol esters and glycidyl esters are not inherently toxic,but the chloropropanol and glycidol produced through their hydrolysis are carcinogenic and/or genetically toxic. Refined vegetable oil is an important ingredient in infant formula,and the infants fed only with milk formula may be exposed to glycidol and MCPD. The fat content of infant formula is higher than those of older infant formula and infant formula,so the contamination level of 3- and 2-MCPD esters is higher. This paper compared the changes in MCPD and glycidol contents in infant formula produced by five US manufacturers from 2013 to 2019. The detection methods of chloropropanol esters and glycidyl esters can be roughly divided into direct methods and indirect methods. At present,there is no limit standard for chloropropanol and glycidyl ester in food in China,but 3-MCPDs and glycidyl esters in vegetable oil and infant formula milk powder can be controlled by referring to EU regulations for the time being.
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