Ketosis is a common disease in the dairy industry,which not only reduces milk production and lowers milk quality but also leads to postpartum diseases,causing significant losses. Ketosis in dairy cow is primarily associated with factors such as inadequate feed energy,abnormal fat metabolism,excessive exercise or stress,diseases or pressure,and improper management. Failure to prevent or treat this disease in a timely manner can result in severe economic losses to the dairy industry. This paper provided an overview of ketosis in dairy cow,focusing on the factors causing ketosis the relationship between ketosis and postpartum diseases,and measures for prevention and treatment,aiming to provide guidance for healthy breeding practices in China's dairy industry.
WANG Bin, BAI Qingling
. Factors Influencing Ketosis in Dairy Cow and the Relationship with Postpartum Diseases[J]. China Dairy, 2023
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DOI: 10.12377/1671-4393.23.06.10
[1] Gao X X,Zhang X,Jiang L Q,et al.Forsythin inhibits 8-hydroxybutyrate-induced oxidative stress in bovine macrophages by regulating p38/ERK,PI3K/Akt,and Nrf2/HO-1 signaling pathways[J]. Research in Veterinary Science,2023,154:59-63.
[2] Lei M A C,Simoes J. Invited review:Ketosis diagnosis and monitoring in high-producing dairy cows[J]. Dairy,2021,2(2):303-325.
[3] 刘宗平. 现代动物营养代谢病学[M]. 北京:化学工业出版社, 2003.
[4] McArt J A A,Nydam D V,Ospina P A,et al. A field trial on the effect of propylene glycol on milk yield and resolution of ketosis in fresh cows diagnosed with subclinical ketosis[J]. Journal of Dairy Science, 2011,94:6011-6020.
[5] 安彦昊,马学虎,孙奕烁,等. 代谢组学在筛选奶牛酮病生物标志物中的应用[J].动物营养学报, 2022,34(8):4829-4835.
[6] 赵善江,郝海生,刘云祥,等. 疾病对奶牛繁殖性能的影响及其研究进展Ⅲ:营养代谢性疾病[J].中国畜牧兽医,2020,47(11):3618-3625.
[7] 郭晓丽. 奶牛酮病的病因、病状与防控措施[J]. 今日畜牧兽医, 2022,38(7):114-115.
[8] 杨春,王艳琼.浅谈奶牛酮病的发病机理及防治措施[J]. 畜禽业, 2022,33(5):117-119.
[9] 肖劲邦,朱颍琨,钱柏霖,等. 围产前期奶牛血清相关能量平衡指标和脂肪因子对酮病的预警作用及意义[J]. 中国农业大学学报. 2019,24(9):79-87.
[10] Shen L,Qian B,Xiao J,et al.Characterization of serum adiponectin and leptin in healthy perinatal dairy cows or cows with ketosis,and their effects on ketosis involved indices[J]. Polish Journal of Veterinary Sciences,2020,23(3):373-381.
[11] 李欣,童津津,赵佳桢,等. 氧化应激、炎症和免疫失衡三方联动效应与奶牛常见健康问题的联系及使用植物提取物进行干预的研究进展[J]. 动物营养学报,2021,33(12):6666-6675.
[12] Ma Y F,Wu Z H,Gao M,et al.Nuclear factor erythroid 2-related factor 2 antioxidant response element pathways protect bovine mammary epithelial cells against H2O2-induced oxidative damage in vitro[J]. Journal of Dairy Science,2018,101(6):5329-5344.
[13] Ma Y F,Wu Z H,Gao M,et al.Nuclear factor erythrocyte 2-related factor 2 antioxidant activation through the action of ataxia telangiectasia-mutated serine/threonine kinase is essential to counteract oxidative stress in bovine mammary epithelial cells[J]. Journal of Dairy Science,2018,101(6):5317-5328.
[14] 薛俊欣,张铮臻,黄克和,等. 奶牛亚临床酮病对乳房炎发病情况和抗氧化功能的影响[J]. 中国兽医学报,2012,32(12):1876-1881.
[15] 夏成,张洪友. 营养对奶牛围产期健康的影响[J]. 黑龙江八一农垦大学学报,2010,22(5):44-50.
[16] 陈喜莹,范明赫,白洪旭,等. Ⅰ型和Ⅱ型酮病奶牛系统性炎症和肝损伤状态的分析与比较[J]. 中国兽医学报,2021,41(4):770-774.
[17] Najm N A,Zimmerman L,Dietrich O, et al.Associations between motion activity, ketosis risk and estrus behavior in dairy cattle[J]. Preventive Veterinary Medicine,2020,175:1-29.
[18] 张萌,刘国林,李向龙,等. 运动对围产期奶牛血液生化指标及免疫指标的影响[J]. 中国兽医学报,2020,40(1):153-161.
[19] Durrer M,Mevissen M,Holinger M,et al.Effects of a multicomponent herbal extract on the course of subclinical ketosis in dairy cows—a blinded placebo-controlled field-study[J].Planta Medica,2020,86(18):1375-1388.
[20] Dorn K,Leiber F,Sundrum A,et al.A field trial on the effects of pure sodium propionate and a combination with herbal extracts on short term development of subclinical ketosis[J]. Livestock Science, 2016,187:87-95.
