This paper delved into the application of Buserelin in timed artificial insemination （TAI） protocols for dairy cattle,while also elaborating on strategies for improving conception rates and its use in treating ovarian disorders. Additionally,a comparative analysis is conducted between Buserelin and Gonadorelin,highlighting their functional differences,mechanisms of action,and respective advantages in applicable scenarios thereby revealing the unique role and value of Buserelin in dairy cattle reproduction. Through extensive and rigorous field trial data,this study evaluated the practical efficacy of Buserelin. Furthermore it explored the potential impact of this product on early pregnancy embryo loss in dairy cows,integrating other reproductive technologies to mitigate the risk of early embryonic loss and enhance reproductive efficiency and economic benefits. By providing an in-depth analysis of Buserelin’s pharmacological mechanisms and empirical research on its practical application in dairy reproduction,this paper aimed to offer scientifically sound methods and strategies for efficient breeding in the dairy industry,promoting more scientific,efficient,and sustainable development in dairy farming.
GUO Zhijian
,
LI Qiang
. Application of Buserelin in Dairy Cattle Reproduction Production[J]. China Dairy, 2025
, 0(6)
: 14
-20
.
DOI: 10.12377/1671-4393.25.06.03
[1] 代涛,尹志峰,赵红玲,等.布舍瑞林的合成[J].中国新药杂志,2014,23(15):1806-1810.
[2] 顾文源,苏硕青,刘玉,等.布舍瑞林在奶牛同期发情-定时输精中的应用效果分析[J].中国畜牧杂志,2021,57(5):149-153.
[3] 琚滢蓥, 徐宏伟, 叶小惠,等.布舍瑞林的研究概述[J]. 海峡药学,2014,26(4):12-14.
[4] 佟太锋. 布舍瑞林的液相全合成研究[D]. 北京:北京化工大学,2006.
[5] Diskin M G,Murphy J J,Sreenan J M.Embryo survival in dairy cows managed under pastoral conditions[J]. Animal Reproduction Science,2006,96(3-4):297-311.
[6] Wijma R,Stangaferro M L,Kamat M M,et al.Embryo mortality around the period of maintenance of the corpus luteum causes alterations to the ovarian function of lactating dairy cows[J]. Biology of Reproduction,2016,95(5):112.
[7] Dailey R A,Inskeep E K,Lewis P L.Pregnancy failures in cattle:a perspective on embryo loss[C]//Proceedings of the 18th International Conference on Reproduction of Farm Animals. Slovakia,2002:1-8.
[8] Puget C,Joueidi Y,Bauville E,et al.Serial HCG and progesterone levels to predict early pregnancy outcomes in pregnancies of uncertain viability:a prospective study[J]. European Journal of Obstetrics & Gynecology and Reproductive Biology,2018,220:100-105.
[9] Ortega H H,Díaz P U,Salvetti N R,et al.Follicular cysts:a single sign and different diseases. A view from comparative medicine[J]. Current Pharmaceutical Design,2016,22(36):5634-5645.
[10] Pesántez J L,Ortiz O,Hernández-Cerón J.Incidence of ovarian follicular cysts and their effect on reproductive performance in dairy cows:A case study in Mexico[J]. Austral Journal of Veterinary Science,2016,48(3):289-291.
[11] Roman L,Broshkov M,Popova I,et al.Influence of ovarian follicular cysts on reproductive performance in the cattle of new Ukrainian red dairy breed[J]. Ukrainian Journal of Ecology,2020,10(2):426-434.
[12] Cook D L,Woods G L,Smith C A,et al.Secretory patterns of LH and FSH during development and hypothalamic and hypophysial characteristics following development of steroid-induced ovarian follicular cysts in dairy cattle[J]. Reproduction,1991,91(1):19-28.
[13] 邵亚群,李强.布舍瑞林在治疗奶牛卵巢囊肿中的应用[J].中国乳业,2024(5):49-52.
[14] Beam S W,Butler W R.Effects of energy balance on follicular development and first ovulation in postpartum dairy cows[J]. Journal of Reproduction and Fertility-Supplement,1999: 411-424.
[15] Ijaz A,Fahning M L,Zemjanis R.Treatment and control of cystic ovarian disease in dairy cattle:A review[J].British Veterinary Journal,1987,143(3):226-237.
[16] Bierschwal C J,Garverick H A,Martin C E,et al.Clinical response of dairy cows with ovarian cysts to GnRH[J].Journal of Animal Science,1975,41:1660-1665.
[17] Picard-Hagen N,Lhermie G,Florentin S,et al.Effect of gonadorelin,lecirelin,and buserelin on LH surge,ovulationand progesterone in cattle[J].Theriogenology, 2015,84(2):177-183.
[18] Probo M,Comin A,Mollo A,et al.Reproductive performance of dairy cows with luteal or follicular ovarian cysts after treatment with buserelin[J].Animal Reproduction Science, 2011,127(3/4):135-139.
