China Dairy ›› 2026, Vol. 0 ›› Issue (6): 21-29.doi: 10.12377/1671-4393.26.06.03

• RUMINANT NUTRITION AND HEALTH • Previous Articles     Next Articles

Biological Functions of Algal Polysaccharides and their Application and Prospects in Dairy Goat Production

WANG Xugan, XU Xiaolong, AN Xiaopeng*   

  1. College of Animal Science and Technology,Northwest A&F University,Yangling Demonstration Zone,Xianyang Shaanxi 712100
  • Online:2026-06-25 Published:2026-07-22

Abstract: Driven by the dual strategies of the comprehensive "antibiotic ban" in feed and the "low-carbon" transformation of animal husbandry developing natural,green and efficient antibiotic-substitute feed additives has become an urgent demand for the sustainable development of the breeding industry. As natural active macromolecules derived from marine algae,algal polysaccharides have become one of the research hotspots in the field of feed additives due to their unique structural characteristics and multi-dimensional biological functions.This paper systematically reviewed the classification, structural characteristics and core biological functions of brown algae,red algae,green algae and microalgae polysaccharides. This paper reviewed the research progress of their application in monogastric animal and ruminant production,focusing on their application potential and mechanisms in regulating rumen fermentation, enhancing immune function,improving lactation performance and maintaining intestinal health in dairy goats. This paper identified the key problems existing in current research and industrial application,and proposed targeted future research directions and industrial application suggestions,aiming to provide a systematic theoretical reference for the scientific application of algal polysaccharides in the green and healthy breeding of dairy goats.

Key words: algal polysaccharides, dairy goat, antibiotic replacement, green feed additive, production performance, intestinal health

[1] 马新燕,李大刚,余苗,等.饲用抗生素替代品在畜禽生产中应用研究进展[J].动物营养学报,2024,36(12):7502-7512.
[2] 孙福昱,南雪梅,唐志文,等.海藻在畜牧生产中应用研究进展[J].中国畜牧兽医,2019,46(1):157-165.
[3] Hindu S V, Chandrasekaran N, Mukherjee A, et al.A review on the impact of seaweed polysaccharide on the growth of probiotic bacteria and its application in aquaculture[J].Aquaculture International,2019,27:227-238.
[4] 赵鹏,李承环,代悦,等.饲粮中添加海藻在反刍动物甲烷排放和生产应用中的研究进展[J].中国饲料,2024(19):20-25,32.
[5] 张燕,史健.海藻多糖对育肥肉羊生长性能、肉品质和肌肉脂肪酸组成的影响[J].中国饲料,2025(14):61-64.
[6] 杨恬,王明明,郑继康,等.减少反刍动物甲烷排放:从饲粮调整到放牧优化[J].畜牧兽医学报,2026,57(2):624-637.
[7] 中华人民共和国农业部.中华人民共和国农业部公告第2625号:关于修订《饲料添加剂安全使用规范》的公告[J].广东畜牧兽医科技,2018,43(1):1.
[8] 冀莎莎,巩鑫,聂慧,等.海藻多糖的分子组成及免疫调节活性研究进展[J].中国食物与营养,2025,31(12):82-87.
[9] 李伟豪,尚秀国,朱晓萍,等.岩藻多糖的生理功能及在畜禽生产中的应用研究进展[J].畜牧兽医学报,2025,56(2):568-578.
[10] 王鹏,陈心怡,耿怡雯,等.浒苔多糖的生物学功能及其在动物生产中的应用研究进展[J].中国畜牧杂志,2024,60(9):66-70.
[11] Jia H F,Li Y Y,Zheng Y P, et al.Recent advances in fucoidan-based improved delivery systems:Structure, carrier types and biomedical applications[J]. Carbohydrate Polymers, 2025, 352:123183.
[12] Udayakumar S, Girigoswami A, Girigoswami K.Biological activities of carrageenan from red algae:A mini review[J]. Current Pharmacology Reports, 2024, 10: 12-26.
[13] Souza R B,Frota A F, Silva J, et al.In vitro activities of kappa-carrageenan isolated from red marine alga Hypnea musciformis: Antimicrobial, anticancer and neuroprotective potential[J]. International Journal of Biological Macromolecules, 2018, 112: 1248-1256.
[14] Ray B.Polysaccharides from Enteromorpha compressa: Isolation, purification and structural features[J]. Carbohydrate Polymers, 2006, 66(3): 408-416.
[15] Wassie T, Niu K, Xie C, et al.Extraction techniques, biological activities and health benefits of marine algae Enteromorpha prolifera polysaccharide[J]. Frontiers in Nutrition, 2021, 8: 747928.
[16] Qian Y M, Ma Y Y, Li W, et al.Screening of a readily selenium-enriched Spirulina polysaccharide and characterization of its structure and bioactivity[J]. Algal Research, 2024, 79: 103682.
[17] Afzal O, Gupta G, Kazmi I, et al.The potential, challenges, and prospects of the genus Spirulina polysaccharides as future multipurpose biomacromolecules[J]. International Journal of Biological Macromolecules, 2024, 268(2):131717.
[18] 刘永童. 日粮添加海藻多糖对断奶仔猪生长性能、血清生化指标和免疫功能的影响[J].中国饲料,2023(24):42-45.
[19] 林海川. 海藻寡糖对仔猪生产性能、免疫功能和盲肠微生物的影响[D].泰安:山东农业大学,2022.
[20] 杨晋. 海藻多糖替代抗生素对断奶仔猪生长性能和肠道屏障功能的影响[D].南昌:江西农业大学,2019.
[21] 曲元凯,李明潭,臧建军.海带酶解液对断奶仔猪生长性能、肠道形态和微生物组成的影响[J].动物营养学报,2024,36(9):5566-5580.
[22] 王立男. 海藻多糖对育肥猪生长性能、屠宰性能和组织微量元素含量的影响[J].中国饲料,2025(4):33-36.
[23] Liu W C, Zhu Y R, Zhao Z H, et al.Effects of dietary supplementation of algae-derived polysaccharides on morphology, tight junctions, antioxidant capacity and immune response of duodenum in broilers under heat stress[J]. Animals, 2021, 11(8): 2279.
[24] Liu W C, Yang Y Y, Pushparaj K, et al.Evaluation of hepatic detoxification effects of Enteromorpha prolifera polysaccharides against aflatoxin B1 in broiler chickens[J]. Antioxidants, 2022, 11(9): 1757.
[25] 迟玉华,金风英,李晓英,等.海藻多糖海藻粉饲料添加剂对肉鸡生长及免疫功能影响的研究[J].畜牧兽医科学(电子版),2022(2):5-6.
[26] 孙文悦. 海藻多糖对SPF鸡免疫功能及ALV-K复制作用研究[D].泰安:山东农业大学,2021.
[27] 丁梦霞. 海藻硫酸多糖对应激诱导的鸡脾脏炎症反应的影响[D].郑州:河南农业大学,2023.
[28] 郭广振,杨伟光,刘娟,等.岩藻多糖对断奶羔羊生长性能、器官指数及血清生化、抗氧化和免疫指标的影响[J].动物营养学报,2022,34(5):3122-3131.
[29] 李连涛. 海带水解物对绵羊采食与消化的影响及其机理研究[D].泰安:山东农业大学,2022.
[30] 李秀芝. 不同生物活性物质对湖羊生长性能、瘤胃微生态及屠宰性能的影响[D].南宁:广西大学,2023.
[31] Mahdi Z A.Effect of sodium alginate on the quality of frozen buffalo semen[J]. IOP Conference Series: Earth and Environmental Science, 2023, 1262: 072085.
[32] Zhao J, Tian H, Kong X, et al.Microbiomic and metabolomic insights into the mechanisms of alfalfa polysaccharides and seaweed polysaccharides in alleviating diarrhea in pre-weaning Holstein calves[J]. Animals, 2025, 15(4): 485.
[33] 李银姝,林茜,龚乃霞,等.海藻多糖结构、生物活性和提取技术研究进展[J].化学试剂,2025,47(5):56-65.
[34] 王胜男,杨伟光,尹福泉.岩藻多糖对断奶羔羊瘤胃微生物区系及代谢组学的影响[J].动物营养学报,2023,35(3):1827-1840.
[35] 郭善军. 红藻提取物对体外瘤胃发酵特性、产甲烷和微生物生长的影响[J].中国饲料,2020(6):54-57.
[36] 潘坛,史怀平,罗军.日粮中添加海藻粉对西农萨能奶山羊生产性能、乳脂肪酸组成、血液代谢指标及瘤胃发酵的影响[C]//中国畜牧兽医学会养羊学分会.2018年全国养羊生产与学术研讨会论文集. 2018:144.
[37] Liu Y L, Zhou M, Diao Q Y, et al.Seaweed as a feed additive to mitigate enteric methane emissions in ruminants: Opportunities and challenges[J]. Journal of Integrative Agriculture, 2025, 24(4): 1327-1341.
[38] Wanapat M, Prachumchai R, Dagaew G, et al.Potential use of seaweed as a dietary supplement to mitigate enteric methane emission in ruminants[J]. Science of the Total Environment, 2024, 931: 173015.
[39] Bahramzadeh S, Tabarsa M, You S G, et al.Purification, structural analysis and mechanism of murine macrophage cell activation by sulfated polysaccharides from Cystoseira indica[J]. Carbohydrate Polymers, 2019, 205: 261-270.
[40] Jayawardena T U, Sanjeewa K K A, Nagahawatta D P, et al. Anti-inflammatory effects of sulfated polysaccharide from Sargassum swartzii in macrophages via blocking TLR/NF-κB signal transduction[J]. Marine Drugs, 2020, 18(12): 601.
[41] Yan W, Luo J, Yu Z, et al.A critical review on intestinal mucosal barrier protection effects of dietary polysaccharides[J]. Food & Function, 2024, 15(2): 481-492.
[42] Boulho R, Marty C, Freile-Pelegrín Y, et al.Antiherpetic (HSV-1) activity of carrageenans from the red seaweed Solieria chordalis (Rhodophyta, Gigartinales) extracted by microwave-assisted extraction (MAE)[J]. Journal of Applied Phycology, 2017, 29: 2219-2228.
[43] 车小蛟,雷宏东,高军军.不同水平岩藻多糖对羔羊生长性能、免疫力及抗氧化功能的影响[J].饲料研究,2022,45(17):13-16.
[44] 郭广振,陈佳怡,彭苏,等.岩藻多糖对断奶羔羊小肠组织形态、消化酶活性和抗氧化指标的影响[J].动物营养学报,2022,34(8):5206-5218.
[45] Cui M Y, Li X H, Geng L H, et al.Comparative study of the immunomodulatory effects of different fucoidans from Saccharina japonica mediated by scavenger receptors on RAW 264.7 macrophages[J]. International Journal of Biological Macromolecules, 2022, 215: 253-261.
[46] 李盛楠,王晶,于玮洁,等.几种褐藻多糖硫酸酯的提取、成分分析及抗氧化活性研究[J].海洋科学,2023,47(3):106-115.
[47] Lekshmi V S, Arun A R, Kurup G M.Sulfated polysaccharides from the edible marine algae Padina tetrastromatica attenuates isoproterenol-induced oxidative damage via activation of PI3K/Akt/Nrf2 signaling pathway[J]. Chemico-Biological Interactions, 2019, 308: 258-268.
[48] 罗光宏,王海蓉,崔晶,等.微波辅助低共熔溶剂提取、部分纯化螺旋藻多糖及其体外生物学活性研究[J].食品与发酵工业,2022,48(11):107-113.
[49] Lu X X, Qin L, Guo M, et al.A novel alginate from Sargassum seaweed promotes diabetic wound healing by regulating oxidative stress and angiogenesis[J]. Carbohydrate Polymers, 2022, 289: 119437.
[50] Fan S Y, Xu Y, Wang L, et al.Sargassum horneri fucoidan oligosaccharide: Purification, characterization, and antioxidant effects targeting the MAPK and KEAP1-NRF2 signaling pathways[J]. Algal Research, 2024, 84: 103756.
[51] Kapahi A, Sankar A A, Gokhale J S.Optimization of sequential ultrasound-microwave assisted extraction of polysaccharide from red seaweed (Kappaphycus alvarezii)[J]. Journal of Applied Phycology, 2024, 36: 3675-3687.
[52] Qi Y G, Zheng T H, Liu X H, et al.Sodium acetate regulates milk fat synthesis through the activation of GPR41/GPR43 signaling pathway[J]. Frontiers in Nutrition, 2023, 10: 1098715.
[53] Harahap M A, Widodo S, Handayani U F, et al.Examining performance, milk, and meat in ruminants fed with macroalgae and microalgae: A meta-analysis perspective[J]. Tropical Animal Health and Production, 2024, 56: 243.
[54] Mi J, Jing X, Ma C, et al.A metagenomic catalogue of the ruminant gut archaeome[J]. Nature Communications, 2024, 15: 9609.
[55] 王志,李彦卿,庄伟,等.多糖微量元素络合物的饲料化应用研究进展[J].化工学报,2021,72(7):3478-3487.
[56] Zhou Z X,Ding Y,Cai R,et al.Preparation and activity evaluation of zinc ion delivery system based on fucoidan-zinc complex[J].Biointerphases,2024,19(5):051007.
[57] 王嘉麟,吴鹏鑫,王胜男,等.饲粮中添加岩藻多糖对羔羊生长性能、肠道消化酶活性和微生物区系的影响[J].动物营养学报,2023,35(4):2417-2430.
[58] Huang J, Huang J L, Li Y, et al.Sodium alginate modulates immunity, intestinal mucosal barrier function, and gut microbiota in cyclophosphamide-induced immunosuppressed BALB/c mice[J]. Journal of Agricultural and Food Chemistry, 2021, 69(25): 7064-7073.
[59] Wijesekara T, Huang R, Wong I, et al.Insights into immunoregulatory effects of bioactive polysaccharides derived from seaweeds through gut microbiota[J]. Food Bioscience, 2024, 58: 103800.
[60] Zhou B F, Jiang J M, Huo Y, et al.Extraction of Chlorella polysaccharide using natural deep eutectic solvent[J]. Algal Research, 2025, 90: 104260.
[61] Shang X C, Chu D P, Zhang J X, et al.Microwave-assisted extraction, partial purification and biological activity in vitro of polysaccharides from bladder-wrack (Fucus vesiculosus) by using deep eutectic solvents[J]. Separation and Purification Technology, 2021, 259: 118169.
[62] 国家卫生健康委员会,国家市场监督管理总局.食品安全国家标准食品中污染物限量:GB2762—2025[S].
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