Abstract: After the melamine incident in 2008,the detection of melamine is very important for the quality control of dairy companies.It is an important monitoring item for the daily work of the quality control department of dairy enterprises.In this paper,the traditional immunological methods,liquid chromatography, mass spectrometry,as well as the more novel near-infrared absorption method,Raman spectroscopy, sensors,electrochemistry and other methods have been combed.Chromatographic methods and immunological methods are more commonly used.Compared with LC-MS/MS or GC-MS (GC-MS/MS) methods,HPLC methods have lower sensitivity;LC-MS/MS or GC-MS (GC-MS)/MS) has high sensitivity,but the instrument is expensive and the detection takes a long time.The immunological detection method is based on the antigen-antibody reaction, and is limited by the specificity of the antibody itself and the interfering components in the sample.The result of the immunological detection product is unstable.Colloidal gold test strips are easy to use and are currently widely used in the industry,but false negatives and false positives are often encountered.ELISA quantitative results are usually more reliable than colloidal gold products.Raman spectroscopy has the advantages of simple pre-processing and fast detection speed,but its sensitivity is lower than that of immunological methods.Polarography,the pre-processing is more cumbersome,and the detection sensitivity.

Key words: melamine, dairy products, detection method