China Dairy ›› 2023, Vol. 0 ›› Issue (6): 79-84.doi: 10.12377/1671-4393.23.06.15

• QUALITY CONTROL • Previous Articles     Next Articles

The Development Status and Prospect of Vitamin K2 in Milk and Dairy Products

LIU Lin, LV Ning, LIN Chao, JIN Nan, LU Yu   

  1. Qingdao Customs Technology Center,Qingdao Shandong 266112
  • Online:2023-06-25 Published:2023-06-30

Abstract: Vitamin K2,an important lipid soluble vitamin,is closely related to human health. At present,only menaquinone-7 is allowed to be used in individual milk powder as a food nutritional fortifier in China. Milk and dairy products are receiving increasing attention as important food source for Vitamin K2 intake.Compare the applicable scope and testing methods specified by current laws and regulations,and put forward targeted countermeasures and suggestions,with a view to providing reference for the monitoring of production enterprises,testing institutions and regulatory departments.

Key words: milk and dairy products, Vitamin K2, development status, prospect

[1] Koshihara Y,Hoshi K,Ishibashi H,et al.Vitamin K2 promotes 1α,25(OH)2 Vitamin D3-induced mineralization in human periosteal osteoblasts[J].Calcified Tissue International,1996,59(6):466-473.
[2] Miyake N,Hoshi K,Sano Y,et al.1,25-Dihydroxyvitamin D3 promotes Vitamin K2 metabolism in human osteoblasts[J].Osteoporosis International,2001,12(8):680-687.
[3] Akedo Y,Hosoi T,Inoue S,et al.Vitamin K2 modulates proliferation and function of osteoblastic cells in vitro[J].Biochemical and Biophysical Research Communications,1992,187(2):814-820.
[4] Geleijnse J M,Vermeer C,Grobbee D E,et al.Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease:The Rotterdam Study[J].The Journal of Nutrition,2004,134(11):3100-3105.
[5] Barbara W,Philip K J,Booth S L,et al.Menaquinones,bacteria,and the food supply:The relevance of dairy and fermented food products to Vitamin K requirements[J].Advances in Nutrition,2013,4(4):463-473.
[6] Beulens J W J,Vander A D L,Grobbee D E,et al.Dietary phylloquinone and menaquinones intakes and risk of Type 2 Diabetes[J].Diabetes Care,2010,33(8):1699-1705.
[7] Shearer M J,Newman P.Recent trends in the metabolism and cell biology of vitaminK with special reference to vitamin K cycling and MK-4 biosynthesis.[J]. Journal of Lipid Research,2014,55(3):345-362.
[8] Okano T,Shimomura Y,Yamane M,et al.Conversion of phylloquinone (Vitamin K1)into menaquinone-4 (Vitamin K2) in mice: two possible routes for menaquinone-4accumulation in cerebra of mice[J]. The Journal of Biological Chemistry,2008, 283(17):11270-11279.
[9] 中国食物成分表2002[M]中国食物成分表2002[M].北京:北京医科大学出版社,2002.
[10] 杨月欣. 中国食物成分表:2004[M].北京:北京大学医学出版社,2005.
[11] 邹连蓬. 食品中维生素K2测定方法的建立与应用[D].北京:中国疾病预防控制中心,2019.
[12] 邹连蓬,张雪松,黄百芬,等.动物性食物不同形式维生素K检测方法的建立[J].卫生研究,2019(5):468-473.
[13] 中华人民共和国国家卫生和计划生育委员会、国家食品药品监督管理局. GB5009.158-2016 食品安全国家标准食品中维生素K1的测定[S].
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