China Dairy ›› 2021, Vol. 0 ›› Issue (10): 61-66.doi: 10.12377/1671-4393.21.10.13

• EXPERIMENTAL STUDY • Previous Articles     Next Articles

Effects of Astragalus Polysaccharide Combined with Yinhuang Soluble Powder on Immunity and Diseases in Neonatal Calves

GUO Sifan, CAO Jie*   

  1. College of Veterinary Medicine,China Agricultural University,Beijing 100193
  • Online:2021-10-25 Published:2021-12-03

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Abstract: To determine the effects of astragalus polysaccharide(APS) combined with Yinhuang soluble powder on immunity and diseases of neonatal calves, 80 neonatal Holstein calves in good health were divided into 2 groups randomly(N=40). The calves in the experimental group were fed with 5 g APS powder and 3 g Yinhuang soluble powder for 7 consecutive days, while the control group was not given any medication. The immune-related indicators were measured at the 7th day and the incidence was observed within 3 weeks. Compared with control group, serum IL-2 concentration of calves in experimental groups increased 8.0% and TNF-α concentration decreased 16.0%. The distribution of T cell lymphocyte subsets improved, and the CD4/CD8 value increased 6.0%. Serum total protein and IgG increased 0.28 g/dL and 0.24 mg/ mL respectively. Incidence rate of calf diarrhea was significantly reduced 15.0% (P < 0.05) in low-risk farm within 7 days and 35.0% (P < 0.05) in high-risk farm within 8~21 d. For respiratory diseases,incidence and disease index were significantly reduced 30.0% (P < 0.05) in high-risk farm. APS combined with Yinhuang soluble powder can effectively improve the immunity of neonatal calves and reduce the incidence of respiratory diseases and diarrhea.

Key words: astragalus polysaccharide, yinhuang soluble powder, calves, diarrhea, respiratory diseases

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