China Dairy ›› 2022, Vol. 0 ›› Issue (6): 55-59.doi: 10.12377/1671-4393.22.06.12

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Application of Sulfonamides Residues in Milk by High Performance Liquid Chromatography

GAO Shuang   

  1. Panjin Inspection and Testing Center,Panjin Liaoning 124010
  • Online:2022-06-25 Published:2022-07-06

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Abstract: Sulfonamides are a kind of synthetic antibiotics with simple use,low price,stable properties and wide antibacterial spectrum. However,long-term or excessive use will lead to drug resistance,toxic and side effects. They can enter the human intestine through the food chain and affect human immune function. High performance liquid chromatography is an efficient screening method with sensitivity,precision and accuracy. The detection of sulfonamides residues is helpful to improve the safety of milk products. This paper firstly introduced the mechanism of action,drug resistance,adverse reactions and detection significance of sulfonamides,and summarized the maximum residue limits and detection applications of sulfonamides in milk,provided reference for the application of high performance liquid chromatography in the detection of sulfonamide drug residues in milk.

Key words: milk, sulfonamides, high performance liquid chromatography, detection method, application

CLC Number: 

  • S859.84
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