China Dairy ›› 2021, Vol. 0 ›› Issue (9): 3-7.doi: 10.12377/1671-4393.21.09.02

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Mechanism and Regulation of Urea Decomposition by Bacterial Urease

XIONG Zhanbo, ZHAO Shengguo, WANG Jiaqi   

  1. State Key Laboratory of Animal Nutrition,Institute of Animal Sciences, Chinese Academy of Agricultural Sciences,Beijing 100193
  • Online:2021-09-25 Published:2021-09-29

Abstract: Urease can efficiently catalyze urea decomposition and produce carbon dioxide and ammonia. Limiting urease activity can effectively regulate urea decomposition process.In animal husbandry,ruminant urease can lead to excessive nitrogen emission.In this paper,the structural characteristics of urease activity center in bacteria,the mechanism of urease hydrolysis and the mechanism of urease activity regulation by inhibitors were reviewed,providing theoretical basis for effective regulation of urease activity and ideas for the development of new inhibitors.

Key words: bacterial urease, urea decomposition, urease inhibitors, inhibition mechanism, ruminant, rumen

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