China Dairy ›› 2026, Vol. 0 ›› Issue (6): 134-140.doi: 10.12377/1671-4393.26.06.17

• QUALITY CONTROL • Previous Articles     Next Articles

Research on the Method for Determining the Contents of 4 Types of Sugar Alcohols in Infant Formula by Ion Chromatography

TANG Chunfu1, LIU Lan1, ZHOU Zhou2, YU Jing1   

  1. 1. Hunan provincial institute of product and goods quality inspection,Hunan Changsha 410007;
    2. Changsha institute for food and drug control,Hunan Changsha 410006
  • Online:2026-06-25 Published:2026-07-22

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Abstract: [Objective] To establish an ion chromatography method for the determination of xylitol,erythritol,sorbitol and maltitol in infant formula.[Method] Dionex CarboPacTM MA1 sugar column guard column（4 mm×50 mm）and Dionex CarboPacTM MA1 sugar analysis column（4 mm×250 mm）were used as chromatographic columns,480mmol/L sodium hydroxide eluent was used for isocratic elution,the flow rate was 0.45mL/min,the injection volume was 10μL,the column temperature was 30℃,and the electrochemical detector was detected.[Results] The mass concentration showed a good linear relationship with its peak area in the range of 0.2~20 μg/mL（r2≥0.99969）,the detection limit was between 0.01~0.20 μg/mL,the average recovery rate was 91.8%~99.1%,and the relative standard deviation（RSD）was in the range of 0.9%~2.9%.[Conclusion] This method was simple to operate,had high sensitivity and good stability,and could provide a reference for the quality control of infant formula.

Key words: ion chromatography, infant formula, xylitol, erythritol, sorbitol, maltitol

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