中国乳业 ›› 2023, Vol. 0 ›› Issue (7): 113-119.doi: 10.12377/1671-4393.23.07.22

• 乳品加工 • 上一篇    

合生元儿童成长奶粉功能性评价

袁紫晴1, 陶芷茵1, 孙晓霞2, 潘锦蓉2, 林沁2, 林绮琪2, 郑倩望1,*   

  1. 1 华南农业大学食品学院,广东广州 510640;
    2 合生元(广州)健康产品有限公司,广东广州 510610
  • 出版日期:2023-07-25 发布日期:2023-08-07
  • 通讯作者: *郑倩望(1988-),女,广东汕头人,工学博士,副教授,研究方向为食品科学。
  • 作者简介:袁紫晴(1999-),女,广东中山人,硕士在读;陶芷茵(1998-),女,广东广州人,微生物学硕士。

Functional Evaluation of Biostime Children's Growth Milk Powder

Yuan Ziqing1, Tao Zhiyin1, Sun Xiaoxia2, Pan Jinrong2, Lin Qin2, Lin Qiqi2, Zheng Qianwang1,*   

  1. 1College of Food Science & Institute of Food Biotechnology, South China Agricultural University, Guangzhou 510640, China;
    2Biostime (Guangzhou) Health Products Limited,Guangzhou 510610,China
  • Online:2023-07-25 Published:2023-08-07

摘要: [目的]对比两种成分不同的奶粉对大鼠的生长状况和骨骼健康的影响。[方法]试验使用了21 只4 周龄SD雄性大鼠,随机分为对照组、奶粉组,奶粉组包括合生元儿童成长奶粉(金盖)(简称“金盖组”)和合生元儿童成长奶粉(蓝盖)(简称“蓝盖组”),用对应饲料进行为期8 周的喂养,探究奶粉添加对大鼠体重、骨密度、骨强度、血清钙及机体免疫的影响。[结果]奶粉组大鼠的摄食量减少,体重维持在正常水平,与对照组无显著差异;两种奶粉均可显著提高大鼠的骨强度,其中金盖组的效果要高于蓝盖组;两种奶粉对大鼠骨皮质骨密度和骨小梁骨密度的增强效果不明显;两种奶粉均可增加大鼠的骨小梁厚度并降低骨小梁分离度,显示出对大鼠骨骼有良好的骨代谢调节能力;金盖组因含有低聚半乳糖(GOS)可帮助促进钙的吸收,血清钙含量比蓝盖组要高;奶粉组大鼠的IgM值相比对照组均有显著提高,而蓝盖组奶粉展现出更强的调节效果,可能与其含有的DHA有关。[结论]两款奶粉在增强骨强度,调节骨代谢及提高机体免疫力上具有良好的效果。

关键词: 合生元儿童成长奶粉, 骨密度, 骨强度, 骨代谢, 机体免疫

Abstract: [Objective] This study compared the effects of two different ingredients of milk powder on the growth status and bone health of rats. [Method] Twenty-one 4-week-old SD male rats were randomly divided into control group and milk powder group. The milk powder group included Biostime Children's Growth milk powder (Golden)(hereinafter referred to as Golden Group) and Biostime Children's Growth Milk powder (Blue)(hereinafter referred to as Blue group),and the corresponding diets were fed for 8 weeks. To explore the effects of milk powder supplementation on body weight,bone density,bone strength,serum calcium and immunity in rats.[Result] The food intake of the rats in the milk powder group was reduced,and the body weight was maintained at the normal level,which had no significant difference with the control group. Both kinds of milk powder can significantly improve the bone strength of rats,and the effect of Golden group is higher than Blue group. The effects of two kinds of milk powder on cortical bone mineral density and trabecular bone mineral density of rats were not obvious;Both kinds of milk powder can increase the thickness of bone trabecular and reduce the degree of bone trabecular separation,which shows that the bone metabolism of rats has a good regulation ability. The content of serum calcium in Golden group was higher than that Blue group because GOS could promote calcium absorption. Compared with the control group,IgM values of the milk powder group were significantly increased, and the milk powder of the Blue group showed a stronger regulatory effect,which may be related to the DHA content.[Conclusion] The two kinds of milk powder have good effects on enhancing bone strength, regulating bone metabolism and improving body immunity.

Key words: Biostime children growth milk powder, bone strength, bone metabolism, body immunity

[1] Lau E M C,Lynn H,Chan Y H,et al. Benefits of milk powder supplementation on bone accretion in Chinese children[J]. Osteoporosis International,2004,15(8):654-658.
[2] Cadogan J,Eastell R,Jones N,et al.Milk intake and bone mineral acquisition in adolescent girls:randomised,controlled intervention trial[J]. BMJ,1997,315(7118):1255.
[3] 史珅,李昊虬,王龙,等. 3种乳制品对低免疫力模型斑马鱼免疫功能的影响[J]. 食品科学,2022,43(11):113-120.
[4] 邓颖妍,李雄超,张晓洁,等. 我国市售儿童奶粉营养素含量分析[J]. 食品工程,2021(4):53-57.
[5] 马爱平. 奶粉新国标落地让国产奶粉更适合中国婴幼儿[N]. 科技日报,2023-03-03.
[6] Seijo M,Bonanno M S,Vénica C I,et al.A yoghurt containing galactooligosaccharides and having low-lactose level improves calcium absorption and retention during growth:experimental study[J]. International Journal of Food Science & Technology,2022,57(1):48-56.
[7] 蒋晨,周刊,侯晓华. 益生元效应:回顾与展望[J]. 临床消化病杂志,2017,29(3):176-179.
[8] Lönnerdal B,Iyer S.Lactoferrin:Molecular Structure and Biological Function[J]. Annual Review of Nutrition,1995,15(1):93-110.
[9] Åbrink M,Larsson E,Gobl A,et al.Expression of lactoferrin in the kidney:Implications for innate immunity and iron metabolism[J]. Kidney International,2000,57(5):2004-2010.
[10] Na Y J,Han S B,Kang J S,et al.Lactoferrin works as a new LPS-binding protein in inflammatory activation of macrophages[J]. International Immunopharmacology,2004,4(9):1187-1199.
[11] 蒋迪. 饲料中不同水平DHA对中华鳖稚鳖生长、消化及血液生理生化指标的影响[D]. 湖南农业大学,2017.
[12] Kunz C,Rudloff S,Baier W,et al.Oligosaccharides in human milk:structural,functional,and metabolic aspects[J]. Annual Review of Nutrition,2000,20(1):699-722.
[13] 周水岳,杭远欣,张岩春,等. 配方奶粉中添加益生元对SD大鼠生长性能、血液生化指标和养分表观消化率的影响[J]. 动物营养学报,2018,30(12):5164-5173.
[14] 张圆圆. 低聚半乳糖、低聚果糖及D-甘露醇对肉仔鸡生长性能、肠道指标及肉品质的影响[D]. 内蒙古农业大学,2022.
[15] Johnell O,Kanis J A,Oden A,et al.Predictive value of BMD for hip and other fractures[J]. Journal of Bone and Mineral Research,2005,20(7):1185-1194.
[16] 李太锡,邓国英. 图像识别技术在骨质疏松诊断中的应用[J]. 国际骨科学杂志,2019,40(3):131-135.
[17] 魏占英,章振林. Micro-CT在骨代谢研究中骨微结构指标的解读及应用价值[J]. 中华骨质疏松和骨矿盐疾病杂志,2018,11(2):200-205.
[18] Florencio-Silva R,Sasso G R D S,Sasso-Cerri E,et al. Biology of bone tissue:structure,function,and factors that influence bone cells[J]. BioMed Research International,2015,:421746.
[19] 李海枝,田巧基,韩晓峰,等. 益生元促钙吸收作用的研究进展[J]. 食品科技,2020,45(9):51-56.
[20] 陈兰芳,肖亮,杨军平. 细胞自噬的分子机制及其功能[J]. 实验与检验医学,2014,32(2):157-163.
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