[目的]为了解牛副结核病在山东省规模牛场的发病和流行情况。[方法]本研究采用血清学检测方法,抽检山东省25 个牛场（13 个奶牛场、12 个肉牛场）血清样品738 份（奶牛血清383 份,肉牛血清355 份）,进行牛副结核病抗体检测。[结果]25 个牛场中有12 个牛场存在牛副结核病抗体阳性,群体阳性率为48.00%。738 份样品中35 份为阳性,个体阳性率为4.74%。表明牛副结核病在山东省部分规模化牛场普遍存在。[结论]此次流行病学调查基本摸清山东省部分规模化牛场牛副结核病的感染情况,为今后该病防控提供参考依据。

[Objective] To investigate the incidence and prevalence of Bovine Paratuberculosis in large-scale cattle farms in Shandong Province. [Method] In this study, 738 serum samples (383 cow serum, 355 beef serum) were collected from 25 cattle farms (13 dairy farms, 12 beef cattle farms) in Shandong Province by serological detection method to detect Bovine Paratuberculosis antibody. [Result] Bovine Paratuberculosis antibody was positive in 12 of the 25 cattle farms, and the population positive rate was 48.00%. 35 of the 738 samples were positive, and the individual positive rate was 4.74%. The results indicated that Bovine Paratuberculosis was widespread in some large-scale cattle farms in Shandong province. [Conclusion] This epidemiological survey basically found out the infection situation of cattle Paratuberculosis in some large-scale cattle farms in Shandong province, and provided reference for the prevention and control of the disease in the future.