[目的] 探索中药复方灌注剂对奶牛乳房炎致病菌的体外抑菌效果及临床疗效。[方法] 通过体外抑菌试验探究中药复方灌注剂的最小抑菌浓度。临床治疗中将120 头患有乳房炎的奶牛,分成4 组,每组10 头,每组4 个重复,分别为对照组、低剂量组、中剂量组、高剂量组。对照组只饲喂基础日粮,低剂量组、中剂量组、高剂量组在饲喂基础日粮基础上,分别灌注10 mL、20 mL、30 mL中药复方灌注剂,21 天后检测乳中体细胞数量（SCC）、患病奶牛体温、采食量、产奶量。[结果] 中药复方灌注剂对金黄色链球菌、链球菌、大肠杆菌抑菌效果为中度敏感,可显著降低乳房炎关键致病菌繁殖活性（P>0.05）。中药复方灌注剂可显著降低7 天、14 天和21 天奶牛乳中SCC,可在临床治疗中降低奶牛乳房炎症状（P>0.05）。与对照组相比,低剂量组、中剂量组、高剂量组可显著降低患乳房炎奶牛体温（P>0.05）;低剂量组、中剂量组、高剂量组可显著提高患乳房炎奶牛采食量（P>0.05）;低剂量组、中剂量组、高剂量组可显著提高患乳房炎奶牛产奶量（P>0.05）。[结论] 中药复方灌注剂可显著抑制金黄色链球菌、链球菌、大肠杆菌繁殖,降低患乳房炎奶牛乳中SCC,降低体温,提高采食量、产奶量。不仅治疗乳房炎,还可提高奶牛健康水平。

[Objective] To explore the bacteriostatic effect and clinical efficacy of Chinese herbal compound infusion on pathogenic bacteria of dairy cow mastitis in vitro. [Method] The minimum bacteriostatic concentration of Chinese medicine compound infusion was investigated by bacteriostatic experiment in vitro. In vivo treatment,120 cows with mastitis were divided into 4 groups with 10 cows per group and 4 replicates per group,which were control group,low dose group, medium dose group and high dose group.The control group was fed only the basal diet,and the low dose group,the medium dose group and the high dose group were fed the basal diet with 10 mL, 20 mL and 30 mL of Chinese herbal compound infusion. the number of somatic cells （SCC） in milk, temperature,feed intake and milk yield were detected 21 days later. [Result] Chinese herbal compound infusion was moderately sensitive to Streptococcus aureus,Streptococcus and Escherichia coli,and could significantly reduce the reproductive activity of key pathogenic bacteria of mastitis（P> 0.05）. The Chinese herbal compound infusion could significantly reduce the SCC in milk of dairy cows at 7,14 and 21 days,and reduce the symptoms of udder inflammation in dairy cows during clinical treatment（P> 0.05）. Compared with the control group, low dose group, medium dose group and high dose group could significantly reduce the body temperature of cows with mastitis（P> 0.05）. Low dose group, medium dose group and high dose group could significantly increase the feed intake of cows with mastitis（P> 0.05）. Low dose group,medium dose group and high dose group could significantly increase milk yield of cows with mastitis（P> 0.05）. [Conclusion] Chinese herbal compound infusion could significantly inhibit the reproduction of Streptococcus aureus,Streptococcus and Escherichia coli,reduce the SCC in milk of cows with mastitis,lower body temperature,and increase feed intake and milk production. It can not only treat mastitis, but also improve the health level of cows.