饲养管理

黄芪多糖对奶牛生产性能、抗氧化能力和免疫功能的影响

  • 李克芳
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  • 沂水县动物疫病预防控制中心,山东临沂 276400
李克芳(1973-),女,山东临沂人,本科,高级兽医师,研究方向为兽医。

网络出版日期: 2026-05-22

Effects of Astragalus Polysaccharides on Production Performance,Antioxidant Capacity and Immune Function of Dairy Cows

  • LI Kefang
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  • Yishui County Animal Disease Prevention and Control Center,Shandong Linyi 276400

Online published: 2026-05-22

摘要

[目的]探讨黄芪多糖对奶牛生产性能、抗氧化能力和免疫功能的影响,为提高奶牛养殖效益及健康管理提供理论依据。[方法]选取72 头胎次、泌乳量及体况相似的奶牛,随机分为4组:对照组(CON)、低剂量组(APS 1.5)、中剂量组(APS 3.0)和高剂量组(APS 4.5)。对照组饲喂基础日粮,其余三组在基础日粮中分别添加1.5、3.0、4.5 g/kg黄芪多糖。预试期15 d,正试期60 d,期间监测并分析产奶量、乳成分、抗氧化指标及免疫指标。[结果]APS 3.0组日产奶量显著提高,乳蛋白率、乳脂率及干物质含量有所改善,体细胞数显著降低;各试验组血清总抗氧化能力(T-AOC)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性显著升高,丙二醛(MDA)含量显著降低;添加黄芪多糖组免疫球蛋白IgA、IgM含量显著提高,肿瘤坏死因子-α(TNF-α)含量显著降低,且中剂量组效果最优。[结论]黄芪多糖能显著提升奶牛生产性能,增强抗氧化能力和免疫功能,其中3.0 g/kg添加量效果最佳,具有较高的养殖应用价值。

本文引用格式

李克芳 . 黄芪多糖对奶牛生产性能、抗氧化能力和免疫功能的影响[J]. 中国乳业, 2026 , 0(4) : 33 -38 . DOI: 10.12377/1671-4393.26.04.06

Abstract

[Objective] To investigate the effects of Astragalus polysaccharides on production performance, antioxidant capacity and immune function of dairy cows,and to provide theoretical basis for improving dairy cattle breeding efficiency and health management. [Method] Seventy-two cows with similar first litter,milk production and body condition were selected and randomly divided into four groups:control group (CON),low-dose group (APS 1.5),medium-dose group (APS 3.0) and high-dose group (APS 4.5).The control group was fed the basal diet,and the other three groups were fed the basal diet supplemented with 1.5,3.0,and 4.5 g/kg Astragalus polysaccharide,respectively.The pre-experimental period lasted 15 d,and the formal experimental period lasted 60 d.during which milk production,milk composition,antioxidant indicators and immune indicators were monitored and analyzed. [Result] Milk production in the APS 3.0 group was significantly improved,milk protein rate,milk fat rate and dry matter content were improved,and somatic cell number was significantly reduced;serum total antioxidant capacity (T-AOC),superoxide dismutase (SOD),glutathione peroxidase (GSH-Px) activities were significantly increased,and malondialdehyde (MDA) content was significantly reduced in each experiment group;The immunoglobulin IgA and IgM contents in the astragalus polysaccharide-supplemented groups were significantly increased,while the tumor necrosis factor-α (TNF-α) content was significantly decreased,with the medium-dose group showing the optimal effect. [Conclusion] Astragalus polysaccharide cansignificantly improve the production performance of dairy cows,enhance antioxidant capacity and immune function,among which 3.0 g/kg addition has the best effect and has high application value in breeding.

参考文献

[1] 赵晏,雷英鹏.枸杞多糖对奶牛生产性能、瘤胃发酵参数、血清抗氧化及免疫能力的影响[J].中国饲料,2024(10):43-46.
[2] 杨希文,祁效林,金国栋,等.柴胡提取物对奶牛生产性能、抗氧化能力及免疫功能的影响[J].现代畜牧科技,2025(5):1-4.
[3] 丁元增. 黄芪多糖对奶牛乳房炎和乳品质的影响[J].中国乳业,2024(6):75-79.
[4] 齐紫伊. 黄芪多糖复合饲料添加剂对犊牛生长性能、血液指标以及粪便菌群的影响[D].大庆,黑龙江八一农垦大学,2024.
[5] Sun Y,Wang X,Zhou H,et al.Dietary A stragalus polysaccharides ameliorates the growth performance,antioxidant capacity and immune responses in turbot (Scophthalmus maximus L.)[J]. Fish & Shellfish Immunol.ogy,2020,99:603-608.
[6] Wu X,Cao N,Zhou Z,et al.Effect of anti-inflammatory compounds or antibiotic administration on receiving performance and physiological responses of transported heifers[J].Journal of Animal Science,2020,98(2):skaa036.
[7] Fan J,Jia F,Liu Y,et al.Astragalus polysaccharides and astragaloside IV alleviate inflammation in bovine mammary epithelial cells by regulating Wnt/β-catenin signaling pathway[J].PLoS One,2022,17(7):e0271598.
[8] Liu T,Zhang M,Niu H,et al.Astragalus polysaccharidefrom Astragalus Melittin ameliorates inflammation via suppressing the activation of TLR-4/NF-κB p65 signal pathway and protects mice from CVB3-induced virus myocarditis[J].International Journal of Biological Macromolecules,2019,126:179-186.
[9] 孙艳,陈鲁喜,陈天荣,等.中草药复方制剂对奶牛生产性能、乳品质和血清指标的影响[J].中国乳业,2025(4):50-54.
[10] 樊嘉琦,贾芳,李宇思,等.黄芪多糖及黄芪甲苷干预对脂多糖诱导的奶牛乳腺上皮细胞炎症的作用[J].华南农业大学学报,2022,43(4):16-28.
[11] 谭春萍,李芳芳,黄裕坚,等.日粮添加黄芪多糖对肉牛生长性能、免疫及抗氧化功能的影响[J].中国饲料,2024(20):19-22.
[12] 杨媛媛,包丽娜,吴树妍,等.药用植物提取物对动物免疫功能影响的研究进展[J].天然产物研究与开发,2025,37(1):168-181.
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