China Dairy ›› 2024, Vol. 0 ›› Issue (12): 82-85.doi: 10.12377/1671-4393.24.12.14

• DISEASE PREVENTION • Previous Articles     Next Articles

Study on Drug Mechanism Characteristics of Multidrug-resistant Staphylococcus aureus of Dairy Cows

ZHANG Shuhua   

  1. Yi Shui County Agricultural Integrated Law Enforcement Team,Linyi Shandong 276400
  • Online:2024-12-25 Published:2025-01-03

Abstract: Staphylococcus aureus is an important pathogenic microorganism,which widely exists in the mammary gland infection of dairy cows,especially mastitis.With the widespread use of antibiotics,Staphylococcus aureus has shown the ability to produce multidrug-resistant(MDR),which has attracted great attention from researchers. In particular,the mechanism of strains isolated from cattle to conventional antibiotics has increased dramatically,which poses a serious threat to the health of dairy cows and the safety of dairy products. The purpose of this paper is to explore the drug mechanism characteristics of multidrug-resistant Staphylococcus aureus of dairy cows,analyze its epidemiology,drug mechanism and prevention and control strategies,and lay a foundation for ensuring the health of dairy cows and the safety of dairy products.

Key words: Staphylococcus aureus, multiple drug mechanism, dairy cow mastitis, antibiotic mechanism

[1] 李琪瑶,王奔.奶牛源多重耐药金黄色葡萄球菌耐药机制研究[J].中国奶牛,2024(6):21-26.
[2] 刘雅红. 多重耐药金黄色葡萄球菌的体内适应性及其机制研究[D].广州:华南农业大学,2020.
[3] Ge B,Mukherjee S,Hsu C H,et al.MRSA and multidrug-resistant Staphylococcus aureus in U.S. retail meats,2010-2011[J].Food Microbiol,2017,62:289-297.
[4] Hoque M N,Talukder A K,Saha O,et al.Antibiogram and virulence profiling reveals multidrug resistant Staphylococcus aureus as the predominant aetiology of subclinical mastitis in riverine buffaloes[J]. Veterinary Medicine and Science,2022,8:2631-2645.
[5] Omwenga I,Aboge G O,Mitema E S,et al.Staphylococcus aureus antimicrobial usage and detection of multidrug-resistant,including Methicillin-resistant strains in raw milk of livestock from Northern Kenya[J].Microb Drug Resist,2021,27:843-854.
[6] 胡方圆,王琳,刘耀蓬,等.我国牛源金黄色葡萄球菌耐药情况及防控研究进展[J].中国动物检疫,2024,41(8):61-68.
[7] Peacock S J,Paterson G K.Mechanisms of methicillin resistance in Staphylococcus aureus[J].Annual Review of Biochemistry,2015,84:577-601.
[8] Sahreena L,Zhang K.Methicillin-resistant Staphylococcus aureus:Molecular characterization,evolution,and epidemiology[J].Clinical Microbiology Reviews,2018,31(4):0.
[9] Hawkey P M,Jones A M.The changing epidemiology of resistance[J].Journal of Antimicrobial Chemotherapy,2009,null:i3-10.
[10] 韩塔拉. 耐甲氧西林金黄色葡萄球菌对利奈唑胺体外诱导耐药的适应性及分子机制[D].呼和浩特:内蒙古医科大学,2023.
[11] 于晓慧. 外排泵对奶牛乳腺炎金黄色葡萄球菌从耐受到耐药性进化的影响及机制研究[D].咸阳:西北农林科技大学,2023.
[12] 陈诗琪,黄珊,谈琦,等.金黄色葡萄球菌的耐药机制及治疗进展[J].赣南医学院学报,2022,42(9):976-980,990.
[13] 何兴丽,王昭元,周佩瑶,等.奶牛乳房炎金黄色葡萄球菌免疫逃避机制研究进展[J].中国畜牧兽医,2024,51(2):748-758.
[14] 刘焱斌. 恶唑烷酮类抗菌药抗耐药金黄色葡萄球菌生物膜形成的分子机制研究[D].成都:四川大学,2021.
[15] 纪帅奇,乌日娜,张淘崴,等.芽孢杆菌脂肽对金黄色葡萄球菌的抑制机理[J].中国食品学报,1-10[2024-09-20].
[16] 何静怡,崔泽林.噬菌体抗菌治疗在临床成功实施面临的挑战[J].中国生物工程杂志,2024,44(8):142-147.
[17] 高思琦,杨新建,朱德琪,等.抗菌肽PAJE对金黄色葡萄球菌及其SCVs的杀菌作用机制研究[J].中国农业科技导报,2024,26(5):156-166.
[18] 蔡娟娟. 新型β-内酰胺酶抑制剂先导化合物的设计与合成[D].石家庄:河北科技大学,2012.
[19] 张红艳,郑良建,肖慈然,等.成都地区拓扑异构酶基因突变在解脲脲原体对氟喹诺酮类药物耐药中的作用[J].中国皮肤性病学杂志,2024,38(4):430-435.
[20] 魏雯静. 细菌外膜囊泡包覆抗生素纳米粒的构建及其抗生物膜感染的研究[D].重庆:重庆理工大学,2024.
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