中国乳业 ›› 2019, Vol. 0 ›› Issue (9): 59-62.

• 质量安全 • 上一篇    下一篇

乳酸菌胞外多糖的分类及生物活性研究进展

黄承敏1, 陈绮1, 游善兵2, 姚慧2, 肖茜1, 刘成国1, 周辉1,*   

  1. 1 湖南农业大学食品科技学院;
    2 湖南南山牧业有限公司
  • 出版日期:2019-09-25 发布日期:2021-03-19
  • 通讯作者: *周辉(1980-),男,博士,副教授,研究方向为食品生物技术。
  • 作者简介:黄承敏(1992-),女,硕士,研究方向为食品生物技术。
  • 基金资助:
    湖南省科技计划项目(2017GK4032); 国家自然科学基金面上项目(31571811)

  • Online:2019-09-25 Published:2021-03-19

摘要: 乳酸菌胞外多糖是乳酸菌在生长代谢过程中分泌的一种糖类化合物,根据多糖的组成,胞外多糖可以分为同型多糖和杂多糖。目前已有研究表明,乳酸菌胞外多糖具有抗氧化、抗肿瘤、调节免疫力等多种生物活性。对乳酸菌胞外多糖的分类及生物活性进行综述,为其开发利用提供参考。

关键词: 乳酸菌, 胞外多糖(EPS), 分类, 生物活性

[1] Majamaa H,Isolauri E,Saxelin M,et al.Lactic acid bacteria in the treatment of acute rotavirus gastroenteritis[J]. Journal of Pediatric Gastroenterology and Nutrition,1995,20(3):333-338.
[2] 刘晶,杨森,陈杨扬,等. 副干酪乳杆菌VL8产胞外多糖条件优化及其抗氧化性质[J]. 中国食品学报,2017,17(5):82-89.
[3] Zajšek K,Goršek A,Kolar M.Cultivating conditions effects on kefiran production by the mixed culture of lactic acid bacteria imbedded within kefir grains[J]. Food Chemistry,2013,139(1-4):970-977.
[4] Badel S,Bernardi T,Michaud P.New perspectives for Lactobacilliexopolysaccharides[J]. Biotechnology Advances,2011,29(1):54-66.
[5] Caggianiello G,Kleerebezem M,Spano G.Exopolysaccharides produced by lactic acid bacteria:from health-promoting benefits to stress tolerance mechanisms[J]. Applied Microbiology and Biotechnology,2016,100(9):3877-3886.
[6] Torino M I,Valdez G F D,Mozzi F. Biopolymers from lactic acid bacteria. Novel applications in foods and beverages[J]. Frontiers in Microbiology, 2015,6(9):834.
[7] Salama Y, Chennaoui M, Sylla A,et al.Characterization,structure, and function of extracellular polymeric substances(EPS)of microbial biofilm in biological wastewater treatment systems:a review[J]. Desalination and Water Treatment,2016,57(35):16220-16237.
[8] Mende S,Rohm H,Jaros D.Influence of exopolysaccharides on the structure,texture,stability and sensory properties of yoghurt and related products[J]. International Dairy Journal,2016,52(1):57-71.
[9] Zannini E,Waters D M,Coffey A,et al.Production,properties,and Industrial food application of lactic acid bacteria-derived exopolysaccharides[J]. Applied Microbiology Biotechnology,2016,100(3):1121-1135.
[10] Kristo E,Miao Z,Corredig M.The role of exopolysaccharide produced by Lactococcuslactis subsp.cremoris in structure formation and recovery of acid milk gels[J]. International Dairy Journal,2011,21(9):656-662.
[11] Ruas-Madiedo P,Hugenholtz J,Zoon P.An overview of the functionality of exopolysaccharides produced by lactic acid bacteria[J]. International Dairy Journal,2002,12(2-3):163-171.
[12] Guo Y X,Pan D D,Sun Y Y,et al.Antioxidant activity of phosphorylated exopolysaccharide produced by Lactococcuslactis subsp.lactis[J]. Carbohydrate Polymers,2013,97(2):849-854.
[13] Shiomi M,Sasaki K,Murofushi M,et al.Antitumor activity in mice of orally administered polysaccharide from Kefir grain[J]. Japanese Journal of Medical Science and Biology,1982,35(2):75-80.
[14] Oda M,Hasegawa H,Komatsu S,et al.Anti-tumor polysaccharide from Lactobacillus sp.[J]. Agricultural and Biological Chemistry,1983,47(7):1623-1625.
[15] Vinderola G,Perdigón G,Duarte J,et al.Effects of the oral administration of the exopolysaccharide produced by Lactobacillus kefiranofaciens on the gut mucosal immunity[J]. Cytokine,2006,36(5-6): 254-260.
[16] Lee D K,Jang S,Kim M J,et al.Anti-proliferative effects ofBifidobacteriumadolescentis SPM0212 extract on human colon cancer cell lines[J]. BMC Cancer,2008,8:1-8.
[17] Ruas-Madiedo P,Hugenholtz J,Zoon P.An overview of the functionality of exopolysaccharides produced by lactic acid bacteria[J]. International Dairy Journal,2002,12(2-3):163-171
[18] 刘宇,孟祥晨. 乳酸菌胞外多糖及其抗肿瘤活性[J]. 中国乳品工业,2008,36(1):39-43.
[19] 邢书涵,连正兴,孙勇,等. 藏灵菇源干酪乳杆菌KL1胞外多糖抑制人结肠癌细胞增殖的研究[J]. 食品科学,2012,33(7):284-288.
[20] 杨焱. 桑黄多糖的分离纯化、结构鉴定和生物活性的研究:[博士论文][D]. 无锡:江南大学,2007.
[21] 顾笑梅,孔建,王富生,等. 一株乳酸菌所产胞外多糖对荷瘤小鼠机体免疫功能影响的研究[J]. 微生物学报,2003,43(2):251-256.
[22] Xu R J,Ye H,Sun Y,et al.Preparation, preliminary characterization,antioxidant,hepatoprotective and antitumor activities of polysaccharides from the flower of tea plant (Camellia sinensis)[J]. Food and Chemical Toxicology,2012,50(7):2473-2480.
[23] Welman A D, Maddox I S.Exopolysaccharides from lactic acid bacteria: perspectives and challenges[J]. Trends in Biotechnology,2003,21(6): 269-74.
[24] Kanmani P,Kumar R S,Yuvaraj N,et a1.Production and purification of a novel exopolysaccharide from lactic acid bacterium Streptococcus phocae PI80 and its functional characteristics activity in vitro[J]. Bioresource Technology,2011,102(7):4827-4833.
[25] Xu R H,Shen Q,Ding X L,et al.Chemical characterization and antioxidant activity of an exopolysaccharide fraction isolated from BifidobacteriumanimalisRH[J]. European Food Research and Technology,2011,232(2):231-240.
[26] 颜炳祥,潘道东,曾小群. 乳酸菌胞外多糖硒化修饰及其抗氧化活性研究[J]. 中国食品学报,2012,12(2):15-23.
[27] 熊强,王凯,王延斌. 植物乳杆菌的功能评价[J]. 生物加工过程,2016,14(6):46-53.
[28] 蔡秋杏,吴燕燕,李来好,等. 来源于腌干鱼的乳酸菌中抗氧化酶及胞外多糖研究[J]. 水产学报,2017,41(6):952-961.
[29] 刘雯雯,孙梦莹,刘丽娜,等. Lactobacillus plantarum- 12菌株胞外多糖培养条件优化及功能特性研究[J]. 食品研究与开发,2018,39(7):180-186.
[30] Patel S,Majumder A,Goyal A.Potentials of exopolysaccharides from lactic Acid bacteria[J]. Indian Journal of Microbiology,2012,52(1): 3-12.
[31] Hidalgo-Cantabrana C, López P,Gueimonde M,et al.Immune modulation capability of exopolysaccharidessynthesised by lactic acid bacteria and Bifidobacteria[J]. Probiotics and Antimicrobial Proteins,2012,4(4):227-237.
[32] Yasuda E,Serata M,Sako T.Suppressive effect on activation of macrophages by Lactobacillus casei strain Shirota genes determining the synthesis of cell wall-associated polysaccharides[J]. Applied and Environmental Microbiology,2008,74(15):4746-4755.
[33] 李伟欣,陈倩,李平兰,等. 一种双歧杆菌胞外多糖免疫调节功能研究[J]. 微生物学通报,2009,36(6):931-935.
[34] Ruas-Madiedo P,Medrano M,Salazar N,et a1. Exopolysaccharides produced by Lactobacillus and Bifidobacterium strains abrogate in vitro the cytotoxic effect of bacterial toxins on eukaryotic cells[J]. Journal of Applied Microbiology,2010,109(6):2079-2086.
[35] Kitazawa H,Harata T,Uemura J,et al.Phosphate group requirement for mitogenic activation of lymphocytes by an extracellular phosphopolysaccharide from Lactobacillus delbrueckii ssp. Bulgaricus[J]. International Journal of Food Microbiology,1998,40(3):169-175.
[1] 赵慧秋, 谷粟琨, 崔明江, 甄理, 张兰峰, 李欣. 不达标生鲜乳的分类处置研究[J]. 中国乳业, 2021, 0(2): 74-76.
[2] 谢婷婷, 黄丽, 黄加祥. 产γ-氨基丁酸的乳酸菌在发酵乳制品中的应用现状[J]. 中国乳业, 2021, 0(1): 60-64.
[3] 郝文文, 兰欣怡. 哺乳动物乳铁蛋白的研究进展[J]. 中国乳业, 2020, 0(9): 78-83.
[4] 刘静龙. 日粮中添加乳酸菌对奶牛酮病及生产性能的影响研究[J]. 中国乳业, 2020, 0(7): 34-37.
[5] 梁超, 杨晓波, 李凯锋. 水牛乳营养成分浅析[J]. 中国乳业, 2020, 0(6): 80-81.
[6] 任秋鸿, 庄超, 彭华. 我国乳制品分类浅析[J]. 中国乳业, 2019, 0(9): 67-69.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!