噬菌蛭弧菌防治犊牛细菌性腹泻的潜力分析

doi:10.12377/1671-4393.23.10.11

摘要/Abstract

摘要： 犊牛细菌性腹泻是困扰犊牛饲养的普遍问题,致病菌耐药性使犊牛细菌性腹泻的预防和治疗更困难,成本更高。噬菌蛭弧菌是一种捕食革兰氏阴性菌的细菌,其捕食范围广,捕食原理使其不受猎物耐药能力影响,有望成为防治犊牛细菌性腹泻的新途径。本文收集近5 年国内犊牛腹泻致病菌及其耐药性研究及近10 年国内外噬菌蛭弧菌捕食、安全性和应用研究,从犊牛腹泻防治的角度进行综述,为噬菌蛭弧菌在犊牛细菌性腹泻的防治和研究提供理论依据和新思路。

关键词: 噬菌蛭弧菌, 犊牛, 肠道致病菌, 腹泻, 耐药性

Abstract: Bacterial diarrhea is a common problem that troubles calf feeding in dairy.The problem of antibiotic resistance of pathogenic bacteria makes the prevention and treatment of bacterial diarrhea more difficult and costly.Bdellovibrio bacteriophage is the bacteria that preys on Gram-negative bacteria and has a wide range of prey. The principle of predation makes it not affected by the antibiotic resistance of prey.Bdellovibrio bacteriovorus may be a new way to prevent and treat bacterial diarrhea in calves.By collecting research on pathogenic bacteria and their antibiotic resistance to calf diarrhea in China in the past 5 years,as well as predation,safety,and application of Bdellovibrio bacteriovorus in China and abroad in the past 10 years,this paper reviewed them from the perspective of prevention and treatment of calf diarrhea.The aim is to provide theoretical basis and new ideas for the prevention and treatment and research of bacterial diarrhea caused by Bdellovibrio bacteriovorus in calves.

Key words: Bdellovibrio bacteriovorus, calf, intestinal pathogenic bacteria, diarrhea, antibiotic resistance

黄萌. 噬菌蛭弧菌防治犊牛细菌性腹泻的潜力分析[J]. 中国乳业, 2023, 0(10): 61-66.

HUANG Meng. The Potential of Bdellovibrio bacteriovorus to Prevent and Treat Bacterial Diarrhea in Calves[J]. China Dairy, 2023, 0(10): 61-66.

参考文献

[1] 鹿书强,刘延国,张琳.细菌性犊牛腹泻分类与防治研究进展[J].饲料博览,2012(7):50-52.
[2] 郭文杰. 引起牛腹泻的细菌性疾病分类辨识诊治[J].畜牧兽医科学(电子版),2022(21):96-98.
[3] 张家瑞,剡文亮,宋洁,等.2020—2021年北疆某规模化奶牛场犊牛腹泻发病情况分析[J].中国牛业科学,2022,48(3):45-48.
[4] 王永强,李偲,耿超,等.通辽地区犊牛腹泻大肠杆菌耐药性检测及一株多重耐药菌全基因组测序分析[J].微生物学通报,2022,49(12):4964-4977.
[5] 周玉照,张小苗,杨晓伟,等.大理地区某规模化乳牛场致犊牛腹泻的病原分析[J].福建畜牧兽医,2022,44(5):38-43.
[6] 吴静,刘涵棋,白婷,等.新疆部分地区犊牛腹泻主要病原调查及分离菌耐药性分析[J].黑龙江畜牧兽医,2022(20):86-92,143.
[7] 党如意,叶超,冯航,等.大肠埃希氏菌和蜡样芽孢杆菌致犊牛腹泻的诊治[J].动物医学进展,2022,43(8):122-125.
[8] 郭双. 通辽地区犊牛腹泻大肠杆菌耐药性检测及一株多重耐药菌株全基因组测序分析[D].通辽:内蒙古民族大学,2022.
[9] 贾垌,张迪,张兆天,等.京津冀部分地区致犊牛腹泻大肠杆菌毒力基因、耐药基因检测及药物敏感性分析[J].中国畜牧兽医,2022,49(12):4820-4831.
[10] 钱英红,贾燕,谢梦圆,等.内蒙古部分地区致犊牛腹泻产肠毒素大肠杆菌的调查研究[J].中国畜禽种业,2023,19(3):109-113.
[11] 张欢,胡朝辉,勾耀鹏,等.4株致病性大肠杆菌致犊牛腹泻的分离鉴定及毒力与耐药性分析[J].中国乳业,2022(12):77-81.
[12] Exner M,Bhattacharya S,Christiansen B,et al.Antibiotic resistance:What is so special about multidrug-resistant Gram-negative bacteria?[J].Gms Hygiene and Infection Control,2017,12(10):5.
[13] Grohmann E.Special issue “multidrug-resistant bacteria in the environment,their resistance and transfer mechanisms”[J].Microorganisms,2023,11(4):981.
[14] 赵朋宽. 河南省濮阳市犊牛腹泻大肠杆菌分离鉴定及生物学特性分析[J].中国动物检疫,2022,39(12):26-30.
[15] Maurmann S C,Fleitas M O,Morales De H,et al.Expanding therapeutic potential of Bdellovibrio bacteriovorus against multidrug-resistant pathogens[J].Drug Discovery Today,2023,28(6):103595.
[16] Sun Y,Ye J,Hou Y,et al.Predation efficacy of Bdellovibrio bacteriovorus on multidrug-resistant clinical pathogens and their corresponding biofilms[J]. Japanese Journal of Infectious Diseases,2017,70(5):485-489.
[17] Dashiff A,Junka R A,Libera M,et al.Predation of human pathogens by the predatory bacteria Micavibrio aeruginosavorus and Bdellovibrio bacteriovorus[J].Journal of Applied Microbiology,2011,110(2):431-444.
[18] Fratamico P M,Whiting R C.Ability of Bdellovibrio bacteriovorus 109J to lyse Gram-negative food-borne pathogenic and spoilage bacteria[J].Journal of Food Protection,1995,58(2):160-164.
[19] Monnappa A K,Dwidar M,Seo J K,et al.Bdellovibrio bacteriovorus inhibits Staphylococcus aureus biofilm formation and invasion into human epithelial cells[J].Scientific Reports, 2014,4:3811.
[20] Im H,Dwidar M,Mitchell R J.Bdellovibrio bacteriovorus HD100,a predator of Gram-negative bacteria,benefits energetically from Staphylococcus aureus biofilms without predation[J].The ISME Journal ,2018 ,12(8):2090-2095.
[21] 洪伟鸣,杨晓志,郁杰,等.一株噬菌蛭弧菌的安全性试验研究[J].黑龙江畜牧兽医,2011(22):106-107.
[22] 王亚丽. 噬菌蛭弧菌的分离、鉴定、培养及其对细菌的抑制作用[D].扬州:扬州大学,2007.
[23] Shatzkes K,Tang C,Singleton E,et al.Effect of predatory bacteria on the gut bacterial microbiota in rats[J]. Scientific Reports,2017,7:43483.
[24] Dwidar M,Monnappa A K,Mitchell R J.The dual probiotic and antibiotic nature of Bdellovibrio bacteriovorus[J].Korean Society for Biochemistry and Molecular Biology - BMB Reports,2012 ,45(2):71-78.
[25] Shatzkes K,Singleton E,Tang C,et al.Examining the efficacy of intravenous administration of predatory bacteria in rats[J].Scientific Reports,2017 ,7(1):1864.
[26] Atterbury R J,Hobley L,Till R,et al.Effects of orally administered Bdellovibrio bacteriovorus on the well-being and Salmonella colonization of young chicks[J].Applied and Environmental Microbiology,2011,77(16):5794-5803.
[27] 陈烨馨,谢梦圆,李文豪,等.牛轮状病毒和志贺菌阳性犊牛腹泻粪便样本中肠道菌群的分析[J].畜牧兽医学报,2023,54(4):1624-1631.
[28] Upatissa S,Mun W,Mitchell R J.Pairing Colicins B and E5 with Bdellovibrio bacteriovorus to eradicate Carbapenem- and Colistin-resistant strains of Escherichia coli[J].Microbiology Spectrum,2023,11(3):e0017323.
[29] Marine E,Milner D S,Lambert C,et al.A novel method to determine antibiotic sensitivity in Bdellovibrio bacteriovorus reveals a DHFR-dependent natural trimethoprim resistance[J].Scientific Reports,2020,10(1):5315.
[30] Hobley L,Summers J K,Till R,et al.Dual predation by Bacteriophage and Bdellovibrio bacteriovorus can eradicate Escherichia coli prey in situations where single predation cannot[J].Journal of Bacteriology,2020,202(6):e00629.

相关文章 15

[1]	王德香, 李红宇, 黄萌, 刘文, 郭春晖, 王树茂, 阿晓辉, 郭立宏, 王佳辉, 王宇. 犊牛开食料的研究[J]. 中国乳业, 2023, 0(8): 39-45.
[2]	李金秀, 刘照雷. 大肠杆菌的分离鉴定及耐药性分析——以山东省临沂市部分奶山羊场为例[J]. 中国乳业, 2023, 0(8): 69-74.
[3]	许凤明. 葛根芩连汤不同配伍对犊牛腹泻的治疗效果分析[J]. 中国乳业, 2023, 0(8): 75-79.
[4]	玄玉莹, 丁玉林, 王金玲. 一例荷斯坦犊牛支原体性肺炎和关节炎的诊断[J]. 中国乳业, 2023, 0(7): 7-9.
[5]	姜久华. 牛病毒性腹泻病毒、牛肠道病毒的流行病学调查分析——以辽宁铁岭地区为例[J]. 中国乳业, 2023, 0(7): 10-13.
[6]	张红梅, 袁溶英, 王峰, 薛海龙, 姬阳. 牛病毒性腹泻的流行病学调查与防控[J]. 中国乳业, 2023, 0(7): 14-17.
[7]	贺泂杰. 交叉引物扩增法快速检测牛病毒性腹泻病毒[J]. 中国乳业, 2023, 0(7): 30-34.
[8]	魏之福, 王振成. 犊牛常见病防治技术的实践与探讨[J]. 中国乳业, 2023, 0(3): 54-59.
[9]	梁文军, 柴聪聪, 李金傲, 梁文涛. 溶菌酶对犊牛腹泻和生长性能的影响[J]. 中国乳业, 2023, 0(2): 40-44.
[10]	曹婧. 奶牛饲养管理与犊牛培育技术探讨[J]. 中国乳业, 2023, 0(10): 48-51.
[11]	郭东芳. 奶山羊乳房炎病原菌分离鉴定与药敏检测分析[J]. 中国乳业, 2023, 0(10): 67-71.
[12]	赵永攀, 汪城, 姜仁娇, 杨红振, 刘东华, 董强. 口鼻污染引起犊牛腹泻的防范[J]. 中国乳业, 2023, 0(1): 45-51.
[13]	姬翠英, 周博文, 周娟, 周春元, 张杰, 张士田, 张娅敏, 何志广, 仇普斌. 高饲料成本下断奶犊牛培育的营养调控措施[J]. 中国乳业, 2022, 0(9): 14-19.
[14]	高雁, 杨胜春, 曾军, 霍向东, 孙建, 林青. 益生菌对断奶后犊牛生长性能及血清指标的影响[J]. 中国乳业, 2022, 0(8): 19-23.
[15]	黄剑锋. 规模奶牛场O型口蹄疫疫苗抗体消长规律研究[J]. 中国乳业, 2022, 0(8): 42-46.

Metrics

Viewed

Full text

Abstract

Cited

Shared

Discussed