奶牛乳腺炎抗生素治疗替代方法综述

doi:10.12377/1671-4393.26.05.10

摘要/Abstract

摘要： 奶牛乳腺炎是奶牛养殖业中常见的炎症性疾病,常导致产奶量下降、经济损失和动物福利问题。传统抗生素治疗虽广泛应用,但易引发耐药性、药物残留及环境污染等挑战。本文旨在系统综述抗生素替代疗法的研究进展,包括非甾体抗炎药疗法、植物提取物药疗法、噬菌体疗法、细菌源抗菌剂、动物源抗菌剂以及其他创新方法如益生菌疗法、基于纳米技术的疗法、光动力疗法（PDT）和声脉冲疗法（APT）,评估了各种疗法的有效性、安全性及临床应用前景,为奶牛乳腺炎的防控提供科学依据。

关键词: 奶牛乳腺炎, 非甾体抗炎药疗法, 植物提取物药疗法, 噬菌体疗法, 细菌源抗菌剂, 动物源抗菌剂

Abstract: Bovine mastitis,a prevalent inflammatory disease in dairy farming,frequently causes reduced milk production,economic losses,and animal welfare issues. While traditional antibiotic treatments are widely used, they pose challenges such as drug resistance,drug residues,and environmental pollution. This article systematically reviews the research progress of antibiotic alternatives,including non-steroidal anti-inflammatory drugs（NSAIDs）,plant extract therapies,bacteriophage therapy,bacterial-derived antimicrobial agents, animal-derived antimicrobial agents,and innovative approaches like probiotic therapy,nanotechnology-based therapies, photodynamic therapy（PDT）, and acoustic pulse therapy（APT）. The study evaluates the effectiveness, safety, and clinical application prospects of these therapies, providing a scientific basis for the prevention and control of bovine mastitis.

Key words: bovine mastitis, non-steroidal anti-inflammatory drug therapy, plant extract therapy, bacteriophage therapy, bacterial-derived antimicrobial agent, animal-derived antimicrobial agent

段红宾, 赵新春. 奶牛乳腺炎抗生素治疗替代方法综述[J]. 中国乳业, 2026, 0(5): 63-70.

DUAN Hongbin, ZHAO Xinchun. A Review of Alternative Therapies to Antibiotics for Bovine Mastitis[J]. China Dairy, 2026, 0(5): 63-70.

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