奶牛繁殖与管理专题

乳房炎对奶牛繁殖性能的影响

展开
  • 1 中国农业科学院北京畜牧兽医研究所,北京 100193;
    2 河北省畜牧总站,河北石家庄 050035
王 欢(1995-),女,河北廊坊人,硕士,研究方向为动物遗传育种与繁殖;赵慧秋(1974-),女,河北武安人,硕士,研究员,研究方向为奶牛繁育与饲养管理;谷栗琨(1980-),女,河北宁晋人,本科,正高级兽医师,研究方向为奶牛疾病与牧场智慧化建设;赵善江(1991-),男,山东临沂人,博士,副研究员,研究方向为动物遗传育种与繁殖;胡智辉(1994-),男,河北保定人,硕士,研究方向为动物遗传育种与繁殖;朱 妮(1991-),女,云南大理人,白族,博士,研究方向为动物遗传育种与繁殖;郝海生(1977-),男,北京人,硕士,助理研究员,研究方向为动物遗传育种与繁殖。

网络出版日期: 2023-10-16

基金资助

家畜胚胎工程与繁殖创新团队(ASTIP-IAS06-2016); 财政部和农业农村部国家现代农业产业技术体系(CARS-36); 河北省现代农业产业技术体系创新团队建设(HBCT2023180203)

Influence of Mastitison Reproductive Performance of Dairy Cows

Expand
  • 1Institute of Animal Sciences,Chinese Academy of Agricultural Sciences,Beijing100193;
    2Henbeing Provincial Animal Husbandry Station,Shijiazhuang Hebei 050035

Online published: 2023-10-16

摘要

乳房炎是奶牛产后乳腺组织发生的病变,是奶牛产后最常见的疾病之一,可分为临床乳房炎和亚临床乳房炎。乳房炎不仅严重影响奶牛泌乳性能,增加泌乳奶牛被动淘汰率,而且也对奶牛繁殖性能产生不利的影响。研究表明,奶牛产后泌乳期配种前和(或)妊娠期间患乳房炎可降低人工授精受胎率、增加早期胚胎死亡(妊娠损失)和流产率、增加空怀天数和产犊间隔,从而影响奶牛养殖经济效益。乳房炎主要是通过影响奶牛生殖内分泌、体液免疫和发热等途径影响母牛卵巢机能、子宫机能和子宫内环境,从而影响母牛发情周期和发情表现、胚胎和胎儿发育而影响奶牛繁殖性能。本文综述了乳房炎对奶牛繁殖性能影响及其机制的研究最新进展,以期为提高我国奶牛繁殖性能提供参考。

本文引用格式

王欢, 赵慧秋, 谷栗琨, 赵善江, 胡智辉, 朱妮, 郝海生, 朱化彬 . 乳房炎对奶牛繁殖性能的影响[J]. 中国乳业, 2023 , 0(9) : 12 -17 . DOI: 10.12377/1671-4393.23.09.02

Abstract

Bovine mastitisis a common disease of postpartum lactation cows. It mainly refers to various lesions of the mammary tissue of cows, including clinical mastitis and subclinical mastitis.Various evidences show that mastitis is one of the important factors affecting the reproductive performance of cows.The research shows that the occurrence of mastitis before mating and(or) during pregnancy can increase the calving interval of cows, and it will also lead to the increase of miscarriage rate and elimination rate of cows in severe cases, which will seriously affect the economic benefits of pastures. In this paper,the clinical manifestations of dairy cow mastitis and its effect on the reproductive performance were described,and the possible mechanism of mastitis affecting the reproductive performance of dairy cows was explained,so as to provide references for the prevention of mastitis and the improvement of the health and reproductive performance of dairy cows in China.

参考文献

[1] Contreras G A,Rodríguez J M.Mastitis:comparative etiology and epidemiology[J]. Journal of Mammary Gland Biology and Neoplasia,2011,16(4):339-356.
[2] 战佩泉. 奶牛乳房炎病原及有效防治[J].畜牧兽医科技信息,2019(8):70.
[3] 谢文新. 奶牛乳房炎发病原因、临床症状及防治措施[J].畜牧兽医科学(电子版),2020(2):105-106.
[4] Santos J E P,Cerri R L A,Ballou M A,etal. Effect of timing of first clinical mastitis occurrence on lactational and reproductive performance of Holstein dairy cows[J].Animal Reproduction Science, 2004,80(1-2):31-45
[5] Boujenane I,El Aimani J,By K.Effects of clinical mastitis on reproductive and milk performance of Holstein cows in Morocco[J]. Tropical Animal Health & Production,2015,47(1):207-211.
[6] 刘坤. 大型牛场奶牛繁殖性能调查及提高奶牛受胎率的研究[D].南京:南京农业大学,2012.
[7] Sharma N,Batoo A S,Huma Z I,et al.Impact of mastitis on reproductive performance in dairy animals:A review[J]. Theriogenology Insight,2017,7(1):41-49.
[8] Schrick F N,Hockett M E,Saxton A M,etal. Influence of subclinical mastitis during early lactation on reproductive parameters[J]. Journal of Dairy Science,2001,84(6):1407-1412.
[9] Barker A R,Schrick F N,Lewis M J,etal. Influence of clinical mastitis during early lactation on reproductive performance of Jersey cows[J]. Journal of Dairy Science,1998,81(5): 1285-1290.
[10] Hudson C D,Bradley A J,Breen J E,et al.Associations between udder health and reproductive performance in United Kingdom dairy cows[J].Journal of Dairy Science,2012,95(7):3683-3697.
[11] Risco C A,Donovan G A,Hernandez J.Clinical mastitis associated with abortion in dairy cows[J].Journal of Dairy Science,1999,82(8):1684-1689.
[12] Hertl J A,Groehn Y T,Leach J D G,et al. Effects of clinical mastitis caused by gram-positive and gram-negative bacteria and other organisms on the probability of conception in New York State Holstein dairy cows[J].Journal of Dairy Science,2010,93(4):1551-1560
[13] Fuenzalida M J,Fricke P M,Ruegg P L.The association between occurrence and severity of subclinical and clinical mastitis on pregnancies per artificial insemination at first service of Holstein cows[J].Journal of Dairy Science,2015,98(6):3791-3805.
[14] Risco C A,Donovan G A,Hernandez J .Clinical mastitis associated with abortion in dairy cows[J].Journal of Dairy Science,1999,82(8):1684
[15] Chebel R C,José E P,Reynolds J P,et al.Factors affecting conception rate after artificial insemination and pregnancy loss in lactating dairy cows[J].Animal Reproduction Science,2004,84(3-4):239-255.
[16] Moore D A,Overton M W,Chebel R C,etal. Evaluation of factors that affect embryonic loss in dairy cattle[J].Journal of the American Veterinary Medical Association,2005,226(7):1112-1118.
[17] Hernandez J A, Risco C A, Lima F S,etal. Observed and expected combined effects of clinical mastitis and low body condition on pregnancy loss in dairy cows[J]. Theriogenology,2012,77(1):115-121.
[18] Mullen P A .Bovine medicine:Disease and husbandry of cattle[J].British Veterinary Journal, 1992,148(6):575.
[19] Bar D,Grohn Y T,Bennett G,etal. Effect of repeated episodes of generic clinical mastitis on milk yield in dairy cows[J]. Journal of Dairy Science,2007,90:4643-4653.
[20] 钟华晨,王丽芳,冯小慧,等.奶牛乳房炎的研究进展及防控措施[J].畜牧与饲料科学,2019,40(12):102-107.
[21] 李宝明,戴命子,李学钊.奶牛乳房炎的诊治[J].中国牛业科学,2019,45(6):92-93.
[22] Santos G,Bottino M P,Santos A P C,et al.Subclinical mastitis interferes with ovulation, oocyte and granulosa cell quality in dairy cows[J].Theriogenology,2018,119-214.
[23] Moore D A,Cullor J S,Bondurant R H,etal. Preliminary field evidence for the association of clinical mastitis with altered interestrus intervals in dairy cattle[J].Theriogenology,1991,36(2):257-265.
[24] Dahl M O,Maunsell F P,De Vries A,et al.Evidence that mastitis can cause pregnancy loss in dairy cows:A systematic review of observational studies[J].Journal of Dairy Science,2017:S0022030217307245.
[25] Mccann S M,Kimura M,Karanth S,et al.Nitric oxide controls the hypothalamic-pituitary response to cytokines[J].Neuroimmunomodulation,1997,4(2):98-106.
[26] Mccann S M,Kimura M,Karanth S,et al.The mechanism of action of cytokines to control the release of hypothalamic and pituitary hormones in infection[J].Annals of the New York Academy of Sciences,2010,917:4-18.
[27] Narender K,Manimaran A,Kumaresan A,etal. Mastitis effects on reproductive performance in dairy cattle:A review[J]. Tropital Animal Health and Production,2017,49:663-673.
[28] Townson D H.Regulation of prostaglandin synthesis by interleukin-1 beta in cultured bovine luteal cells[J].Biology of Reproduction,1994,51(3):480-485.
[29] Nakajima Y,Mikami O,Yoshioka M.Elevated levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) activities in the sera and milk of cows with naturally occurring coliform mastitis[J]. Research in Veterinary Science,1997,62(3):297-298.
[30] Hansen P J,Soto P,Natzke R P.Mastitis and fertility in cattle - possible involvement of inflammation or immune activation in embryonic mortality[J]. American Journal of Reproductive Immunology,2004,51(4):294-301.
[31] Shuster D E,Kehrli M E,Stevens M G.Cytokine production during endotoxin-induced mastitis in lactating dairy cows[J]. American Journal of Veterinary Research,1993,54:80-85.
[32] Rainard P,Paape M J.Senstitization of the bovine mammary gland to escherichina coli endotoxin[J]. Veterinary Research,1997,28:231-238.
[33] Hoeben D,Burvenich C,Trevisi E,etal. Role of endotoxin and TNF-alpha in the pathogenesis of experimentally induced coliform mastitis in periparturient cows[J].Journal of Dairy Research,2000,67:503-514.
[34] Paape M J,Rautiainen P M,Lilius E M,etal.Development of anti-bovine TNF-alpha mAb and ELISA for quantitating TNF-alpha in milk after intramammary injection of endotoxin[J]. Journal of Dairy Science,2002,85:765-773.
[35] Persson Waller K,Colditz I G,Lun S,etal. Cytokines in mammary lymph and milk during endotoxin-induced bovine mastitis[J]. Research in Veterinary Science,2003,34(1):31-36.
[36] Rambeaud M,Almerida R A,Pighetti G M,etal. Dynamics of leukocytes and cytokines during experimentally induced streptococcus uberis mastitis[J]. Veterinary Immunology and Immunopathology,2003,96:193-205.
[37] Schams D,Berisha B.Regulation of corpus luteum function in cattle-An overview[J]. Reprod. Domest. Anom,2004,39:241-251.
[38] Soto P,Natzke R P,Hansen P J .Identification of possible mediators of embryonic mortality caused by mastitis: actions of lipopolysaccharide, prostaglandin F2alpha, and the nitric oxide generator, sodium nitroprusside dihydrate, on oocyte maturation and embryonic development in ca[J].AJRI: American Journal of Reproductive Immunology,2003(3):50.
[39] Giri S N,Chen Z,Carroll E J,et al.Role of prostaglandins in pathogenesis of bovine mastitis induced by Escherichia coli endotoxin[J].American Journal of Veterinary Research,1984,45(3):586-591.
[40] Barros C M,Betts J G,Thatcher W W,et al.Possible mechanisms for reduction of circulating concentrations of progesterone by interferon-alpha in cows: effects on hyperthermia, luteal cells,metabolism of progesterone and secretion of LH[J].Journal of Endocrinology,1992,133(2):175.
[41] Giri S N,Emau P,Cullor J S,et al.Effects of endotoxin infusion on circulating levels of eicosanoids,progesterone,cortisol,glucose and lactic acid,and abortion in pregnant cows[J].Veterinary Microbiology,1990,21(3):211-231.
[42] 江仁富. 奶牛乳房炎的特点、诊断及治疗方法[J].当代畜禽养殖业,2019(8):26-27.
[43] Iii C E K,Stephens S H,Hansen P J.Developmental changes in inhibitory effects of arsenic and heat shock on growth of pre-implantation bovine embryos[J].Molecular Reproduction & Development,2002,63(3):335-340.
文章导航

/