中国乳业 ›› 2021, Vol. 0 ›› Issue (9): 67-73.doi: 10.12377/1671-4393.21.09.11

• 饲养管理 • 上一篇    下一篇

饲粮组成对牛乳中乳蛋白及乳脂肪合成与调控机理影响的研究进展

李欣1, 童津津1, 熊本海2, 蒋林树1   

  1. 1 北京农学院动物科学技术学院奶牛营养学北京市重点实验室,北京 102206;
    2 中国农业科学院北京畜牧兽医研究所,北京 100193
  • 出版日期:2021-09-25 发布日期:2021-09-29
  • 通讯作者: *蒋林树(1971-),男,浙江富阳人,博士,教授,博士生导师,研究方向为奶牛营养与免疫。
  • 作者简介:李 欣(1998-),女,内蒙古呼伦贝尔人,硕士,研究方向为反刍动物营养与免疫;童津津(1963-),女,黑龙江哈尔滨人,博士,讲师,研究方向为奶牛营养与免疫;熊本海(1963-),男,湖北红安人,博士,研究员,博士生导师,研究方向为畜牧信息技术。
  • 基金资助:
    北京市教委重点项目(20JF0008)

Research Progress on the Effects of Different Dietary Composition on the Synthesis and Regulation Mechanism of Milk Protein and Milk Fat

LI Xin1, TONG Jinjin1, XIONG Benhai2, JIANG Linshu1,*   

  1. 1Beijing Key Laboratory of Dairy Nutrition, College of Animal Science and Technology, BeijingUniversity of Agriculture, Beijing 102206;
    2Beijing Institute of Animal Science and Veterinary Medicine, Chinese Academy of Agricultural Sciences, Beijing 100193
  • Online:2021-09-25 Published:2021-09-29

摘要: 牛乳中的营养物质对人类健康有着相当大的益处,乳蛋白和乳脂肪作为牛乳营养品质的物质基础,还与奶牛生产性能息息相关,受到人们的广泛关注。本文从牛乳中基本营养物质的种类和功能出发,重点介绍了饲粮组成的改变及添加植物提取物、微量元素、微生态制剂等对乳蛋白及乳脂肪合成与调控机理的影响,为科学合理地调整饲粮营养组成,提高牛乳中乳蛋白率和乳脂率提供理论依据。

关键词: 牛乳, 基本营养物质, 饲粮添加剂, 植物提取物, 微量元素

Abstract: The nutrients in cow's milk have considerable benefits to human health. As the material basis of the nutritional quality of cow's milk, milk protein and milk fat are also closely related to the production performance of dairy cows and have received widespread attention. Starting from the types and functions of basic nutrients in milk, this paper focuses on the effects of changes in diet composition and addition of plant extracts, trace elements, and microecological preparations on the synthesis and regulation mechanism of milk fat and milk protein. To provide theoretical basis for adjusting the nutritional composition of diets and improving the rate of milk protein and milk fat.

Key words: milk, basic nutrients, dietary additives, phytoextracts, trace element

[1] 邓志程,叶为果,巫少芬. 天然生物活性物质及其功能食品的研究进展[J]. 现代食品,2018,5(10):83-85.
[2] 吕贺,段晓宇,周金玉,等. 奶牛乳脂合成及其影响因素[J]. 中国畜牧兽医,2018,45(1):93-99.
[3] Turgeon S L, Brisson G.Symposium review: the dairy matrix-bioaccessibility and bioavailability of nutrients and physiological effects[J]. Journal of Dairy Science, 2020, 103(7): 6727-6736.
[4] 吴建民,王雍,周协琛,等.基于宏基因组学解析瘤胃微生物调节荷斯坦奶牛乳蛋白含量的研究[J]. 动物营养学报,2020,32(8):3843-3855.
[5] Appuhamy J A D R N, Nayananjalie W A, England E M, et al. Effects of AMP-activated protein kinase (AMPK) signaling and essential amino acids on mammalian target of rapamycin (mTOR) signaling and protein synthesis rates in mammary cells[J]. Journal of Dairy Science, 2014, 97(1): 419-429.
[6] 汪东阳,谢月琴,罗君谊,等. 调控乳蛋白合成信号通路的研究进展[J]. 中国奶牛,2020(5):6-11.
[7] Holdorf A D, Lee K H, Burack W R, et al.Regulation of Lck activity by CD4 and CD28 in the immunological synapse[J]. Nat Immunol, 2002, 3(3): 259-264.
[8] Tong J J, Thompson I M, Zhao X, et al.Effect of 17β-estradiol on milk production, hormone secretion and mammary gland gene expression of dairy cows[J]. Journal of Dairy Science, 2017, 101(3): 2588-2601.
[9] Tong J J, Thompson I M, Zhao X, et al.Effect of the concentration of circulating prolactin on dairy cows responsiveness to domperidone injection[J]. Journal of Dairy Science, 2018,101(3):2579-2587.
[10] Barbone D, Yang T M, Morgan J R, et al.Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids[J]. The Journal of biological chemistry, 2008, 283(19): 13021-13030.
[11] Tian Q, Wang H, Wang,M, et al.Lactogenic hormones regulate mammary protein synthesis in bovine mammary epithelial cells via the mTOR and JAK-STAT signal pathways[J]. Animal Production Science, 2016, 56(11): 1803-1809.
[12] 杨德莲,童津津,孙铭维,等. 无乳链球菌通过抑制酪氨酸激酶/信号转导及转录激活因子和哺乳动物雷帕霉素靶蛋白信号通路影响奶牛乳腺上皮细胞乳蛋白的合成[J]. 动物营养学报,2019,31(8):3706-3718.
[13] 刘永峰,张薇,刘婷婷,等. 乳蛋白中乳清蛋白与酪蛋白组成、特性及应用的研究进展[J]. 食品工业科技,2020,41(23):354-358.
[14] Hu L Y, Wang M Z, Ouyang J L, et al.Rapid communication: Period2 gene silencing increases the synthesis of αs-casein protein in bovine mammary epithelial cells[J]. Journal of Animal Science, 2017, 95(10): 4510-4513.
[15] 孙姗姗,李刚,罗娇依,等. 乳粉及乳制品中酪蛋白含量及产地关联性的分析[J]. 中国食物与营养,2019,25(10):20-25.
[16] 王春梅,王保胜,门晶晶,等. 层粘连蛋白调控奶牛乳腺上皮细胞乳蛋白合成途径研究[J]. 东北农业大学学报,2020,51(6):46-53.
[17] 赖淑静,齐瑞利,袁陶燕,等. 奶牛酪蛋白和β-乳球蛋白基因多态及其对泌乳性状的影响[J]. 浙江畜牧兽医,2013,38(1):8-11.
[18] Nakajima K, Itoh F, Nakamura M, et al.Short communication: opposing effects of lactoferrin on the proliferation of fibroblasts and epithelial cells from bovine mammary gland[J]. Journal of Dairy Science, 2015, 98(2): 1069-1077.
[19] 王磊,成雪,毛学英,等. 乳清蛋白及其活性多肽的生物学功能研究进展[J]. 中国农业科技导报,2010,12(5):30-35.
[20] 马露,周凌云,卜登攀,等. 饲粮营养水平对奶牛乳蛋白合成的影响及其作用机理的研究进展[J]. 中国畜牧兽医,2012,39(10):121-127.
[21] Rius A G, Appuhamy J A D R N, Cyriac J, et al. Regulation of protein synthesis in mammary glands of lactating dairy cows by starch and amino acids[J]. Journal of Dairy Science, 2010, 93(7): 3114-3127.
[22] 张振红,马可为,赵国先,等. 饲料营养对牛乳蛋白及乳脂肪的影响[J]. 饲料博览(技术版),2008(5):13-16.
[23] 李琮,臧长江,刘亚伟,等. 添喂两种植物雌激素对奶牛乳成分、血液生化指标和抗氧化性能的影响[J]. 中国畜牧兽医,2017,44(6):1688-1693.
[24] 武开乐,库西塔别克·买买提依不拉音,马静,等. 雌激素对奶牛乳腺上皮细胞中酪蛋白和甘油三酯表达的影响[J]. 饲料工业,2019,40(11):36-42.
[25] 石宁,许晓凯,方洛云,等. 植物提取物对奶牛免疫机能及产奶性能的影响[J]. 中国草食动物科学,2017,37(1):50-54.
[26] 占今舜. 苜蓿黄酮对奶牛生产性能、瘤胃代谢和免疫性能影响的研究:[博士论文][D]. 扬州:扬州大学,2017.
[27] 陈晓梅,徐国庆. 酵母硒对奶牛产奶性能和乳品质的影响[J]. 中国畜禽种业,2019,15(8):85-86.
[28] 苏芮,刘阳,闫素梅,等. 维生素A对奶牛乳腺上皮细胞乳脂和乳蛋白合成相关基因表达的影响[J].动物营养学报,2018,30(8):3151-3158.
[29] 刘洪生. 影响乳成分的日粮调控技术[J]. 中国奶牛,2008(3):22-24.
[30] Bauman D E, Harvatine K J, Lock A L.Nutrigenomics, rumen-derived bioactive fatty acids, and the regulation of milk fat synthesis[J]. Annual Review of Nutrition, 2011, 31(1): 299-319.
[31] Yan Q, Tang S, Zhou C, et al.Effects of free fatty acids with different chain lengths and degrees of saturability on the milk fat synthesis in primary cultured bovine mammary epithelial cells[J]. Journal of Agricultural and Food Chemistry, 2019, 67(31): 8485-8492.
[32] 陈凤香,袁超,包杰. 牛乳脂的组成及结构研究进展[J]. 粮食与油脂,2018,31(7):9-12.
[33] 王慧,方洛云,熊本海,等. 牛乳生物活性成分及其研究进展[J]. 中国乳业,2018(8):62-67.
[34] Molkentin J.Occurrence and biochemical characteristics of natural bioactive substances in bovine milk lipids[J]. British Journal of Nutrition, 2000, 84(Suppl 1): 47-53.
[35] 白晨,哈斯额尔敦,敖长金. 泌乳奶牛乳腺中乳脂肪和乳蛋白合成的互作及其研究进展[J]. 动物营养学报,2014,26(5):1164-1173.
[36] Peterson D G, Matitashvili E A, Bauman D E.Diet-induced milk fat depression in dairy cows results in increased trans-10, cis-12CLA in milk fat and coordinate suppression of mRNA abundance for mammary enzymes involved in milk fat synthesis[J]. Journal of Nutrition, 2003, 133(10): 3098-3102.
[37] Bilik K, Strzetelski J, Dierżuk I F, et al.Effect of supplementing TMR diets with artificial saliva and Acid Buf on optimizing ruminal pH and fermentation activity in cows[J]. Annals of Animal Science, 2014, 14(3): 585-593.
[38] 雷莉辉,于凤芝,孙健. 酵母硒在动物饲养中的应用[J]. 养殖与饲料,2020,19(11):9-11.
[39] Kalscheur K F, Teter B B, Piperova L S, et al.Effect of fat source on duodenal flow of transC18:1fatty acids and milk fat production in dairy cows[J]. Journal of Dairy Science,1997, 80(9): 2115-2126.
[40] 赵小刚,谭支良,汤少勋,等. 奶牛乳脂率降低的生物学机制[J]. 家畜生态学报,2006,27(3):5-9.
[41] Beever D E, Cammell S B, Thomas C, et al.The effect of date of cut and barley substitution on gain and on the efficiency of utilization of grass silage by growing cattle.1.Gains in live weight and its components[J]. The British Journal of Nutrition 1988, 60(2): 307-319.
[42] 王吉峰,王加启. 奶牛营养代谢对乳脂合成调控机制的研究进展[J]. 中国畜牧兽医,2003,30(2):6-10.
[43] 陈光明. 槲皮素对奶牛乳腺上皮细胞抗氧化性能和乳脂合成的影响[J]. 中国饲料,2017(13):16-19.
[44] 宋洁,王丽芳,张腾龙,等. 复合植物提取物对乳腺炎奶牛生产性能、乳品质和免疫机能的影响[J].动物营养学报,2020,32(12):5724-5732.
[45] 黄国欣,张养东,郑楠,等. 奶牛乳脂形成的调控措施及其机理[J]. 饲料工业,2019,40(11):49-53.
[46] 孙满吉,卢德勋,王丽芳,等. 阴外动脉灌注乙酸钠对奶山羊乳腺营养物质摄取和利用的影响[J]. 动物营养学报,2009,21(6):865-871.
[47] 蒋小艺,杨得坡,刘朝亮,等. 乳酸菌制剂对奶牛泌乳量及乳成分的影响[J]. 中国乳品工业,2008,36(4):41-43.
[48] 闫碧川,李振乾,李胜利,等. 不同酵母培养物对泌乳中后期奶牛生产性能、养分表观消化率以及血清指标的影响[J]. 动物营养学报,2018,30(7):2732-2740.
[49] 龚龑,张彬. 反刍动物微生态制剂研究进展[J].中国奶牛,2014(18):8-12.
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