中国乳业 ›› 2025, Vol. 0 ›› Issue (8): 8-14.doi: 10.12377/1671-4393.25.08.02

• 奶牛繁殖健康管理专栏 • 上一篇    下一篇

热应激下奶牛激素调控策略及其应用效果分析

赵新春   

  1. 曹县畜牧服务中心,山东菏泽 274400
  • 出版日期:2025-08-25 发布日期:2025-09-10
  • 作者简介:赵新春(1970-),男 ,山东曹县人,本科,畜牧师,研究方向为畜牧兽医技术。

Regulation Strategies and Application Effects of Hormones in Dairy Cows under Heat Stress

ZHAO Xinchun   

  1. Animal Husbandry Service Center of Cao County, Heze Shandong 274400
  • Online:2025-08-25 Published:2025-09-10

摘要: 热应激对奶牛生产性能、繁殖功能及免疫系统造成显著负面影响,导致产奶量下降15%~20%、受胎率降低25%~35%,并引发多种健康问题。本文系统阐述了热应激对奶牛的影响机制,重点探讨了生殖激素(如GnRH、孕酮)、糖皮质激素(如地塞米松)及褪黑激素等在缓解热应激中的科学应用策略。结合南北地区牧场实际案例,验证了激素调控在提升奶牛抗应激能力、改善繁殖效率及恢复生产性能方面的有效性。研究强调,激素使用应遵循短期、低剂量原则,并配合物理降温和营养调控等综合措施,以确保乳品安全与养殖效益。本文为奶牛场应对热应激提供了理论依据与实践指导。

关键词: 热应激, 奶牛, 激素使用, 管理策略

Abstract: Heat stress exerts significant negative impacts on the production performance, reproductive function, and immune system of dairy cows, leading to a 15%~20% decrease in milk yield, a 25%~35% reduction in conception rate, and various health disorders. This paper systematically elaborated the mechanisms through which heat stress affects dairy cows, with a focus on the scientific application strategies of reproductive hormones (such as GnRH and progesterone), glucocorticoids (such as dexamethasone), and melatonin in alleviating heat stress. Practical cases from dairy farms in both northern and southern regions demonstrate the effectiveness of hormonal regulation in enhancing stress resistance,improving reproductive efficiency, and restoring production performance. The study emphasized that hormone use should adhere to the principles of short-term and low-dose application, combined with comprehensive measures such as physical cooling and nutritional adjustments, to ensure dairy product safety and farming profitability. This paper provides a theoretical basis and practical guidance for dairy farms to mitigate heat stress.

Key words: heat stress, dairy cows, hormone application, management strategies

[1] 可持续发展经济导刊.最新全球气候状况报告速览:人类引发的气候变化达到新高度[EB/OL].https://sdg-china.net/NewsList/info_itemid_70836.html,2025-03-27[2025-07-09].
[2] 李显,宋玉环,张娟,等.生殖激素在奶牛临床上的应用[J].中国畜禽种业,2009,5(5):38-39.
[3] 梁琛,张建海.夏季奶牛热应激的发生及综合防治[J].现代畜牧兽医,2005(8):38-40.
[4] 廖晓霞,叶均安.泌乳奶牛热应激研究进展[J].中国饲料,2005(19):21-23.
[5] 宋代军,何钦,姚焰础.热应激对不同泌乳阶段奶牛生产性能和血清激素浓度的影响[J].动物营养学报,2013,25(10):2294-2302.
[6] 何钦. 热应激对不同泌乳阶段奶牛生产性能及其营养代谢的影响[D].重庆:西南大学,2012.
[7] 张晶,葛楠,赵海明,等. 密云地区夏季热应激对奶牛产奶量影响的调查分析[J].当代畜牧,2017(9):10-11.
[8] 侯引绪,魏朝利.夏季热应激对牛奶成分的影响与应对措施[J].中国奶牛,2014(Z1):10-12.
[9] 杨贞耐,张健.干酪质量安全问题与控制技术[J].食品科学技术学报,2015,33(6):11-17.
[10] Wolfenson D,Roth Z,Meidan R,et al.Impaired reproduction in heat-stressed cattle:basic and applied aspects[J].Animal reproduction science,2000,60-61:535-547.
[11] Roth Z.Heat stress,the follicle,and its enclosed oocyte:mechanisms and potential strategies to improve fertility in dairy cows[J].Reproduction in domestic animals,2008,43(S2):238-244.
[12] Collier R J,Baumgard L H,Zimbelman R B,et al.Heat stress:physiology of acclimation and adaptation[J]. Animal frontiers,2019,9(1):12-19.
[13] De Rensis F,Scaramuzzi R J.Heat stress and seasonal effects on reproduction in the dairy cow—a review[J].Theriogenology,2003,60(6):1139-1151.
[14] García-Ispierto I,López-Gatius F,Bech-Sabat G,et al.Climate factors affecting conception rate of high producing dairy cows in northeastern Spain[J].Theriogenology,2007,67(8):1379-1385.
[15] Sheldon I M,Dobson H. Postpartum uterine health in cattle[J].Animal Reproduction Science,2004,82-83:295-306.
[16] Rhoads M L,Rhoads R P,Vanbaale M J,et al.Effects of heat stress and plane of nutrition on lactating Holstein cows:I. Production,metabolism,and aspects of circulating somatotropin[J].Journal of Dairy Science,2009,92(5):1986-1997.
[17] Harper M E,Seifert E L.Thyroid hormone effects on mitochondrial energetics[J]. Thyroid,2008,18(2):145-156.
[18] Kadzere C T,Murphy M R,Silanikove N,et al.Heat stress in lactating dairy cows: a review[J].Livestock production science,2002,77(1):59-91.
[19] 程广龙. 奶牛热应激的发生及减缓措施[J].安徽农业科学,2008,36(7):2797-2798.
[20] 边小娜,张家新.褪黑激素抗氧化作用的研究进展[J].安徽农学通报,2017,23(9):24-27.
[21] 李卫群,陈钟英,周瑶玺.免疫调节中白细胞介素2和γ-干扰素的相互关系[J].国外医学(免疫学分册),1986(6):312-315.
[22] 杨利国. 下丘脑促性腺激素释放激素的神经内分泌调节[J].黑龙江动物繁殖,1995(4): 39-41.
[23] 田文儒,胡庆德,李俊伟,等.前列腺素F2α对产后奶牛繁殖性能影响的研究[J].辽宁畜牧兽医,1993(4):7-9.
[24] López-Gatius F,López-Béjar M,Fenech M,et al.Ovulation failure and double ovulation in dairy cattle:risk factors and effects[J].Theriogenology,2005, 63(5):1298-1307.
[25] Pugliesi G,Santos F B,Lopes E,et al.Improved fertility in suckled beef cows ovulating large follicles or supplemented with long-acting progesterone after timed-AI[J].Theriogenology,2016,85(7):1239-1248.
[26] Bech-Sabat G,López-Gatius F,Yániz J L,et al.Factors affecting plasma progesterone in the early fetal period in high producing dairy cows[J]. Theriogenology,2008,69(4):426-432.
[27] Friedman E,Voet H,Reznikov D,et al.Hormonal treatment before and after artificial insemination differentially improves fertility in subpopulations of dairy cows during the summer and autumn[J].Journal of Dairy Science,2014,97(12): 7465-7475.
[28] 陈仗榴. 兽医药理学[M].北京:中国农业出版社,2002.
[29] 谭健,余诗强,赵玉超,等.糖皮质激素与热应激奶牛免疫系统互作机制的研究进展[J]. 动物营养学报,2023,35(9):5496-5504.
[30] 李瑾,曾晓.地塞米松的作用及在奶牛疾病治疗中的禁忌[J].畜牧兽医科学(电子版), 2019(7):47-48.
[31] Li Z Q,Zhang K Y,Zhou Y M,et al.Role of melatonin in bovine reproductive biotechnology[J].Molecules,2023,28(13):4940.
[32] Gao Y J,Li Y N,Wang J M,et al.Melatonin alleviates lipopolysaccharide-induced endometritis by inhibiting the activation of NLRP3 inflammasome through autophagy[J].Animals,2023,13(15):2449.
[33] Zhao X M,Wang N,Hao H S,et al.Melatonin improves the fertilization capacity and developmental ability of bovine oocytes by regulating cytoplasmic maturation events[J]. Journal of Pineal Research,2018,64(1):e12445.
[34] Ahmad S B,Ali A,Bilal M,et al.Melatonin and health:Insights of melatonin action,biological functions,and associated disorders[J].Cellular and Molecular Neurobiology,2023,43(6):2437-2458.
[35] Brockus K E,Hart C G,Gilfeather C L,et al.Dietary melatonin alters uterine artery hemodynamics in pregnant Holstein heifers[J].Domestic animal endocrinology,2016,55:1-10.
[36] Ratchanak R,Thananurak P,Boonkum W,et al.The melatonin treatment improves the ovarian responses after superstimulation in Thai-Holstein crossbreeds under heat stress conditions[J].Frontiers in Veterinary Science,2022,9:888039.
[37] 孙伟,郭雅欣,王超,等.褪黑素对高产荷斯坦奶牛体外胚胎生产质量及效率的影响[J].中国畜牧杂志,2025:1-8.
[38] 戴艳菲,王弘浩,张瑞,等.维生素缓解奶牛热应激的研究进展[J].家畜生态学报,2025,46(5):5-10.
[1] 付畅, 李强. 现代牧场繁殖数据深度解析与效率优化策略[J]. 中国乳业, 2025, 0(8): 2-7.
[2] 及美拉. 热应激对奶牛繁殖性能的影响及生殖激素调控策略[J]. 中国乳业, 2025, 0(8): 15-20.
[3] 周长城. 奶牛同期发情处理技术的实践应用与关键管控策略[J]. 中国乳业, 2025, 0(8): 21-26.
[4] 张建波, 黑立新, 裴廷福, 朱高照, 胡智胜. 奶牛葡萄球菌性乳腺炎及其防御机制[J]. 中国乳业, 2025, 0(8): 37-46.
[5] 黄晶. 日粮中添加中草药提取物后对奶牛隐性乳腺炎的防控效果[J]. 中国乳业, 2025, 0(8): 47-53.
[6] 张廷青, 乔治, 吕宏伟. 奶牛早期胚胎死亡的综合研究与精准防控策略[J]. 中国乳业, 2025, 0(7): 6-6.
[7] 谷粟琨, 王振成, 李志佳, 赵善江, 朱化彬, 赵慧秋. 奶牛早期胚胎损失与预防措施[J]. 中国乳业, 2025, 0(7): 12-17.
[8] 刘明胜, 赵平. 奶牛胚胎早期死亡的多因素分析与综合防控技术研究[J]. 中国乳业, 2025, 0(7): 18-23.
[9] 李培明, 李强, 郭志坚, 付畅, 王冬, 马婧蕾. 热应激期间繁殖障碍的诊断和治疗措施[J]. 中国乳业, 2025, 0(7): 31-37.
[10] 李阳, 杨艳芬. “双碳”目标背景下奶牛养殖绿色发展研究[J]. 中国乳业, 2025, 0(7): 46-50.
[11] 朱春燕, 仝静迪, 邓波, 杨丽英, 成晓迅, 宋荣渊, 程佳. 新型补钙剂对奶牛产后低血钙症的防治作用[J]. 中国乳业, 2025, 0(7): 51-59.
[12] 刘来可, 王丽静, 刘桂芹. 2020—2023年山东阳谷县奶畜布鲁氏菌病基线调查报告[J]. 中国乳业, 2025, 0(7): 65-70.
[13] 马祥群. 常见奶牛皱胃疾病的防治[J]. 中国乳业, 2025, 0(7): 77-83.
[14] 蔡锦纯, 李永健, 焦陇玲, 张润泽, 周明, 齐亚银. 奶牛临床型乳房炎主要致病菌的分离鉴定及综合防控——以新疆某规模牧场为例[J]. 中国乳业, 2025, 0(7): 84-89.
[15] 伏广达, 刘维红, 胡智胜. 奶牛乳腺炎金黄色葡萄球菌毒力因子与抗菌素耐药性关系研究进展[J]. 中国乳业, 2025, 0(7): 90-99.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!