多组学技术在奶牛瘤胃微生物与宿主互作机制中的研究进展

doi:10.12377/1671-4393.21.08.13

摘要/Abstract

摘要： 对于反刍动物而言,瘤胃对宿主的新陈代谢、机体免疫调节具有重要的意义。作为瘤胃内强大而丰富的群落,瘤胃微生物结构紊乱不仅会导致生产性能下降,还会引发机体全身炎症反应。近年来,多组学技术分析瘤胃微生物与宿主的关系及其调控机制已逐渐受到研究者的关注。本文从瘤胃微生物的影响因素、多组学技术在瘤胃微生物中的应用及瘤胃微生物紊乱对宿主的影响等多方面进行综述,以通过调节瘤胃微生物来提高奶牛生产性能、增强机体免疫力以及预防疾病等新的视角为奶牛养殖者提供参考。

关键词: 多组学技术, 微生物区系, 瘤胃, 免疫调节, 奶牛疾病

Abstract: For ruminants,the rumen is important for the metabolism of the host and the regulation of the body's immunity.Structural disorders of rumen microorganisms,a powerful and abundant community in the rumen,can lead not only to reduced production performance but also to systemic inflammatory reactions.In recent years,the use of multi-omics techniques to analyze rumen microbial-host relationships and their regulatory mechanisms has gradually received widespread attention from research scholars.Therefore,this paper will review the factors influencing rumen microbes,the application of multi-omics techniques in rumen microbes and the effects of rumen microbial disorders on the host,providing new perspectives on the regulation of rumen microbes to improve dairy cows' performance, enhance body immunity and prevent the occurrence of diseases.

Key words: multi-omics technology, microbiota, rumen, immunomodulation, cow diseases

沈义媛, 童津津, 熊本海, 蒋林树. 多组学技术在奶牛瘤胃微生物与宿主互作机制中的研究进展[J]. 中国乳业, 2021, 0(8): 68-75.

SHEN Yiyuan, TONG Jinjin, JIANG Lingshu, XIONG Benhai. Progress of Multi-omics in Interaction Mechanism Between Rumen Microorganism and Host in Dairy Cows[J]. China Dairy, 2021, 0(8): 68-75.

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