表观性状及产奶相关基因用于筛选高产奶牛的潜在价值

doi:10.12377/1671-4393.23.04.07

摘要/Abstract

摘要： 高产量奶牛的高效选育一直是困扰奶业及奶牛养殖业高效发展的难题,产奶量不足,生产效率不稳定等问题也严重制约了行业的发展。但传统筛选高产奶牛方法耗时耗力,不利于高产奶牛快速培育,且优良性状的遗传稳定性较差,也无法长期保留。目前,越来越多研究发现产奶量与奶牛的表观性状有关,如体重、体尺、乳房形态及肛殖距等。不仅如此,产奶量及奶品质还与催乳素及其受体基因、生长激素及其受体基因、二酰甘油酰基转移酶基因和及其他产奶基因具有密切关系。因此,本文对影响奶牛产奶量的相关因素进行了综合概述,阐述了不同因素对高产奶牛筛选应用的潜在价值,有望促进高产奶牛的快速筛选,助力奶牛养殖业的快速发展。

关键词: 表型性状, 基因, 筛选, 高产奶牛

Abstract: Efficient selection and breeding of high-yielding cows has been a difficult problem for the efficient development of the dairy industry and dairy farming,and problems such as insufficient milk production and unstable production efficiency have also seriously restricted the development of the industry. However,traditional screening methods for high-yielding cows are time-consuming and labor-intensive,not conducive to rapid breeding of high-yielding cows,and the genetic stability of good traits is poor and cannot be retained in the long term.Currently,more and more studies have found that milk yield is related to the cow's apparent traits,such as weight,body size,udder shape and anal spacing.In addition,milk yield and milk quality are also closely related to prolactin and its receptor genes,growth hormone and its receptor genes,diacylglycerol acyltransferase genes and other milk production genes.Therefore,this paper provided a comprehensive overview of the relevant factors affecting milk yield in dairy cows and illustrated the potential value of different factors for the application of high-yielding cow screening,which was expected to facilitate the rapid screening of high-yielding cows and contribute to the rapid development of dairy farming.

Key words: phenotypic traits, genes, screening, high-yielding dairy cows

王宗, 折晓英. 表观性状及产奶相关基因用于筛选高产奶牛的潜在价值[J]. 中国乳业, 2023, 0(4): 51-56.

WANG Zong, SHE Xiaoying. Potential Value of Epistatic Traits and Milk Production-related Genes for Screening High-yielding Cows[J]. China Dairy, 2023, 0(4): 51-56.

参考文献 41

[1]	姜同强,李燕,李芝维.城市消费者对食品安全的需求特征分析——以牛奶需求为例[J].食品科学技术学报,2017,35(6):85-90.
[2]	张智慧,李伟,韩永胜.牛体尺影响因素及其应用[J].中国畜牧杂志,2018,54(1):9-13.
[3]	闫瑞祥. 基于集成学习的奶牛产奶量预测的研究与实现[D].银川:宁夏大学,2022.
[4]	刘亚楠,彭朋,郑伟杰,等.中国荷斯坦牛IGF1R基因对产奶性状的遗传效应分析[J].农业生物技术学报,2021,29(8):1518-1527.
[5]	夏立新. 基于mRNA-miRNA分析的牛乳脂代谢功能基因筛选及KLF6基因功能验证[D].长春:吉林大学,2021.
[6]	张浩,黄锡霞,热西提·阿布都热依木,等.伊犁地区荷斯坦奶牛体尺体重及外貌评分对产奶量的影响[J].新疆农业科学,2010,47(12):2447-2451.
[7]	Berry D P,Evans R D.The response to genetic merit for milk production in dairy cows differs by cow body weight[J].JDS Communications,2022,3(1):32-37.
[8]	Han L,Heinrichs A J,Vries A D,et al.Relationship of body weight at first calving with milk yield and herd life[J].Journal of Dairy Science,2021,104(1):397-404.
[9]	Wood P D P,King J O L,Youdan P G.Relationships between size,live-weight change and milk production characters in early lactation in dairy cattle[J].Animal Production,1980,31(2):143-151.
[10]	张强,梁艳,高启松,等.荷斯坦牛泌乳早期体重与产奶量变化规律研究[J].中国奶牛,2019(9):16-18.
[11]	魏秋玉,高献周.影响奶牛产奶量的关键因素分析[J].安徽农业科学,2005,33(9):1670-1671.
[12]	蔡治华,陈仙平.奶牛体尺与产乳量的相关性分析及产乳量预测[J].当代畜牧,2006(8):35-36.
[13]	程月,毛华明.德宏杂交奶水牛体尺及体重对高峰奶量的影响[J].黑龙江畜牧兽医,2018(7):198-201.
[14]	徐启明. 不同因素对奶牛产奶量的影响研究[J].安徽农学通报,2014,20(16):113-114.
[15]	陈玲,王秀清.宁夏玉美奶牛场荷斯坦牛体型外貌鉴定及产奶性能的分析报告[J].中国乳业,2010(11):26-28.
[16]	虎业浩,张晓雪,胥磊,等.西门塔尔牛乳房形态结构与产奶量的相关性分析.中国畜牧杂志,2023,59(3):144-147,154.
[17]	吴欣悦,卢徐斌,徐天乐,等.苏北地区中国荷斯坦牛体型性状遗传参数及其与产奶性状关系的分析[J].黑龙江畜牧兽医(上半月),2022(7):65-70.
[18]	吴锦波,何世明,艾鷖,等.麦洼牦牛体尺和乳房性状与153 d产奶量的相关性及主成分分析[J].黑龙江畜牧兽医(上半月),2019(3):149-152.
[19]	王兴国,张家贞.应用奶牛乳房参数估测产奶量的探讨[J].青海畜牧兽医杂志,1994,24(2):16-18.
[20]	赵开森,康喆,樊慧梅,等.中国荷斯坦奶牛肛殖距与产奶性能的相关性研究[J].四川农业大学学报,2022,40(5):645-648.
[21]	Atici O K,Govindrajan N,Lopetegui-Gonzalez I,et al.Prolactin:A hormone with diverse functions from mammary gland development to cancer metastasis[J].Seminars in Cell & Developmental Biology,2021,114:159-170.
[22]	Cowan C M,Dentine M R,Ax R L,et al.Structural variation around prolactin gene linked to quantitative traits in an elite Holstein sire family[J].Theoretical and Applied Genetics,1990, 79(5):577-582.
[23]	Dybus,A.Associations of growth hormone (Gh) and prolactin (Prl) genes polymorphisms with milk production traits in Polish Black-and-White cattle[J].Animal Science Papers & Reports,2002,20(4):203-212.
[24]	Alfonso E, Rojas R, José G.Herrera, et al.[J]. African Journal of Biotechnology,2012,11(29):7338-7343.
[25]	Alipanah M,Kalashnikova L,Rodionov G.Association of prolactin gene variants with milk production traits in russian red pied cattle[J].Iranian Journal of Biotechnology,2007,5(3):158-161.
[26]	Thuy N T D,Thu N T,Cuong N H,et al.Polymorphism of pit-1 and prolactin genes and their effects on milk yield in holstein frisian dairy cows bred in vietnam[J].Russian Journal of Genetics,2018,54(3):346-352.
[27]	Brym P,Kaminski S,Wojcik E.Polymorphism within the bovine prolactin receptor gene (PRLR)[J].Animal Science Papers & Reports,2005,23(1):61-66.
[28]	Mohammed A E-M, Aziza F, Khaled A K, et al. Polymorphisms of the PRLR gene and their association with milk production traits in egyptian buffaloes[J].Animals,2021,11(5):1237-1247.
[29]	周震. 荷斯坦奶牛催乳素基因多态性对泌乳性状的影响研究[D].石河子:石河子大学,2022.
[30]	Mohamed A,Ali A,Naif M,et al.Sequencing and polymorphism detection in growth hormone gene in najdi sheep and their association with milk production[J].Indian Journal of Animal Research,2019,53(4):423-428.
[31]	Pozovnikova M V,Rotar L N,Kudinov A A,et al.The linkage of polymorphic variants of genes Gh,Prl,and Pit-1 and milk productivity of cows with morphology of cumulus-oocyte complex sampled post mortem[J].Cytology & Genetics,2020,54(3):212-219.
[32]	Heidari M,Azari M A,Hasani S,et al.Effect of polymorphic variants of Gh,Pit-1,and beta-LG genes on milk production of Holstein cows[J].Genetika,2012,48(4):503-507.
[33]	Bordonaro S,Tumino S,Marletta D,et al.Effect of gh p.l127v polymorphism and feeding systems on milk production traits and fatty acid composition in modicana cows[J].Animals,2020,10(9):1651-1650.
[34]	张海容,吴建平.奶牛群体生长激素基因多态性与产奶量关联性[J].中国兽医学报,2010,30(6):811-814,821.
[35]	马彦男,贺鹏迦,朱静,等.GH基因遗传多态性与中国荷斯坦牛泌乳性状的遗传效应分析[J].中国兽医学报,2013,33(12):1943-1948.
[36]	Samuel B,Mengistie D,Assefa E,et al.Genetic diversity of DGAT1 gene linked to milk production in cattle populations of Ethiopia[J].BMC Genomic Data,2022,23(1):64-73.
[37]	宋天,王大会,刘贤,等.家畜DGAT1基因的生物学功能及其在遗传育种中的应用研究[J].中国牛业科学,2020,46(4):52-56.
[38]	Bernard G,Frédéric F,Latifa K,et al.Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition[J].Proceedings of the National Academy of Sciences,2004,101(8):2398-2403.
[39]	Li F Y,Cai C C,Qu K X,et al.DGAT1 K232A polymorphism is associated with milk production traits in Chinese cattle[J].Animal Biotechnology,2021,32(4):427-431.
[40]	王思伟,王学清,石少轻,等.河北地区中国荷斯坦牛DGAT1基因多态性与泌乳性状遗传效应分析[J].中国奶牛,2019(4):14-20.
[41]	韦张其. DDIT3基因对奶牛产奶性状的遗传效应分析及功能验证[D].合肥:合肥工业大学,2021.

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