乳脂肪球膜对人体健康影响的研究进展

doi:10.12377/1671-4393.26.05.16

摘要/Abstract

摘要： 乳脂肪球膜（MFGM）是天然存在于人乳和牛乳中的保护性膜结构,可通过抑制脂肪团聚和氧化以维持乳液的稳定。MFGM的核心成分由多种极性脂质与功能蛋白组成,具体组成受奶牛日粮组成、品种和健康状态等内源生理因素和外源生产加工因素的影响,导致不同来源的MFGM成分间存在显著差异。近年来,随着研究者对MFGM生理功能与人体健康益处方面的深入研究,尤其是在生命早期脑发育、认知功能、骨骼肌和心脏代谢方面的健康作用被逐步揭示,使MFGM成为营养与食品科学领域的研究热点。本文深入探讨了MFGM的营养与功能特性,重点阐述了最新临床证据,并对MFGM作为功能性食品核心配料的开发前景与发展方向进行展望。

关键词: 乳脂肪球膜（MFGM）, 人体健康, 生理功能, 结构, 分离纯化

Abstract: Milk Fat Globule Membrane（MFGM）is a naturally occurring protective membrane structure present in both human and bovine milk,which maintains the stability of milk emulsions by inhibiting fat aggregation and oxidation. The core components of MFGM are composed of a diverse array of polar lipids and functional proteins. Its specific composition is modulated by both endogenous physiological factors（including the dietary composition,breed,and health status of dairy cows）and exogenous production and processing factors,resulting in significant compositional heterogeneity among MFGM preparations from different sources. In recent years,with in-depth research on the physiological functions of MFGM and its benefits to human health,especially the gradual elucidation of its health-promoting effects on early-life brain development,cognitive function,skeletal muscle and cardiac metabolism,MFGM has emerged as a prominent research hotspot in the field of nutrition and food science. This review provided an in-depth discussion of the nutritional and functional properties of MFGM,highlighted the latest supporting clinical evidence,and offered an outlook on the development prospects and future application directions of MFGM as a core functional ingredient in functional foods.

Key words: milk fat globule membrane（MFGM）, human health, physiological functions, structure, separation and purification

寇春雨, 时阳, 王帅, 粘靖祺, 车佳玲. 乳脂肪球膜对人体健康影响的研究进展[J]. 中国乳业, 2026, 0(5): 111-119.

KOU Chunyu, SHI Yang, WANG Shuai, NIAN Jingqi, CHE Jialing. Advances in Research on the Impacts of Milk Fat Globule Membrane on Human Health[J]. China Dairy, 2026, 0(5): 111-119.

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