婴幼儿配方乳粉高氯酸盐污染风险分析研究

doi:10.12377/1671-4393.24.10.14

中国乳业 ›› 2024, Vol. 0 ›› Issue (10): 78-83.doi: 10.12377/1671-4393.24.10.14

婴幼儿配方乳粉高氯酸盐污染风险分析研究

周密, 马娇, 么赛, 何湘漪, 史娜, 郭蕊, 郑跃, 刘艳申^*

北京市食品检验研究院（北京市食品安全监控和风险评估中心）/国家市场监管重点实验室（食品安全重大综合保障关键技术）,北京 100094

出版日期:2024-10-25 发布日期:2024-11-08
通讯作者: ^*刘艳申（1966-）,男,天津人,本科,高级讲师,研究方向为食品安全。
作者简介:周密（1985-）,女,山西永济人,硕士,工程师,研究方向为食品安全;马娇（1988-）,女,山东泰安人,硕士,工程师,研究方向为食品质量与安全;么赛（1993-）,女,河北唐山人,本科,助理工程师,研究方向为食品安全;何湘漪（1987-）,女,河北衡水人,硕士,高级工程师,研究方向为食品安全与分析;史娜（1982-）,女,河北保定人,本科,高级工程师,研究方向为食品营养与安全;郭蕊（1989-）,女,河北高碑店人,硕士,助理研究员,研究方向为食品工程;郑跃（1989-）,女,北京人,硕士,工程师,研究方向为食品安全分析。
基金资助:
国家市场监督管理总局科技计划项目（2022MK008）

Risk Analysis of Perchlorate Contamination Risk in Infant Formula Milk Powder

ZHOU Mi, MA Jiao, YAO Sai, HE Xiangyi, SHI Na, GUO Rui, ZHENG Yue, LIU Yanshen^*

Beijing Institute of Food Inspection and Research（Beijing Municipal Center for Food Safety Monitoring and Risk Assessment）,Key Laboratory of Key Technologies of Major Comprehensive Guarantee of Food Safety for State Market Regulation,Beijing 100094

Online:2024-10-25 Published:2024-11-08

摘要/Abstract

摘要： 婴幼儿配方乳粉作为婴幼儿主要营养来源之一,我国高度重视其生产和监管。随着乳粉质量提升,可能存在的潜在风险成为关注焦点。污染物高氯酸盐因抑制人体甲状腺功能,尤其影响婴幼儿群体生长发育,引起广泛关注。本文介绍了高氯酸盐的特性、健康风险及相关评估、限量情况,简述了中国、美国、欧盟等国家和地区高氯酸盐污染情况及相关监管、评估研究,为我国婴幼儿配方乳粉高氯酸盐污染风险管理、提高乳粉品质提供参考。

关键词: 高氯酸盐, 婴幼儿配方乳粉, 潜在风险, 食品安全, 风险评估

Abstract: As one of the main nutrition sources for infants,China attach great importance to the production and supervision. With the improvement of infant formular milk powder quality,the potential risks that may exist had become the focus of attention. Perchlorate has caused widespread concern because of its inhibition of thyroid function,especially the influence on growth and development of infants. This paper introduced the characteristics,health risks and related assessments and limits of perchlorate. The situation of perchlorate pollution in China,US,EU and other countries and regions,as well as related supervision and assessment research were briefly introduced. It provided reference for the risk management of perchlorate pollution in infant formula milk powder and the improvement of milk powder quality in China.

Key words: perchlorate, infant formular, potential risk, food safety, risk assessment

周密, 马娇, 么赛, 何湘漪, 史娜, 郭蕊, 郑跃, 刘艳申. 婴幼儿配方乳粉高氯酸盐污染风险分析研究[J]. 中国乳业, 2024, 0(10): 78-83.

ZHOU Mi, MA Jiao, YAO Sai, HE Xiangyi, SHI Na, GUO Rui, ZHENG Yue, LIU Yanshen. Risk Analysis of Perchlorate Contamination Risk in Infant Formula Milk Powder[J]. China Dairy, 2024, 0(10): 78-83.

参考文献

[1] 宇盛好,李亦奇,张旭晟,等.上海市市售食品中高氯酸盐污染的暴露评估[J].上海预防医学,2017,29(6):426-430.
[2] Mcdougal J N,Jones K L,Fatuyi B,et al.The effects of perchlorate on thyroidal gene expression are different from the effects of iodide deficiency[J].Toxicology and Environmental Health A,2011,74(14):917-926.
[3] Agency for Toxic Substances and Disease Registry(ATSDR).Public Health Statement for Perchlorates[EB/OL].https://www.atsdr.cdc.gov/ToxProfiles/tp162-c1-b.pdf,2008-09.
[4] Bernhardt R R,Hippe F A V,Cresko W A.Perchlorate induces hermaphroditism in threespine sticklebacks[J].Environmental Toxicology Chemistry,2006,25(8):2087-2096.
[5] Greer M A,Goodman G,Pleus R C,et al.Health effects assessment for environmental perchlorate contamination:The dose response for inhibition of thyroidal radioiodine uptake in humans[J].Environmental Health Perspectives,2002,110(9):27-34.
[6] Zhang P,Shi Y L,Cai Y Q,et al.Analysis of perchlorate,bromate and iodide in milk using ion chromatography-electrospray tandem mass spectrometry[J].Journal of Instrumental Analysis,2007,26(6):90-98.
[7] 宁钧宇,肖文,魏洪鑫,等.高氯酸盐的危害评估[J].毒理学杂志,2021,35(3):198-214.
[8] 方齐乐,陈宝梁.新型环境污染物高氯酸盐的环境化学行为、食品安全及健康风险[J].科学通报,2013,58(26):2626-2642.
[9] 王诤,付学起.饮用水中的高氯酸盐[J].净水技术,2001,20(4):3-35.
[10] Zhang T,Wu Q,Sun H W,et al.Perchlorate and iodide in whole blood samples from infants,children,and adults in Nanchang,China[J].Environmental Science & Technology,2010,44(18):6947-6953.
[11] Murray C W,Egan S K,Kim H,et al.US food and drug administration’s total diet study:Dietary intake of perchlorate and iodine[J].Journal of Exposure Science and Environmental Epidemiology,2008,18(6):571-580.
[12] Huber D R,Blount B C,Mage D T,et al.Estimating perchlorate exposure from food and tap water based on US biomonitoring and occurrence data[J].Journal of Exposure Science and Environmental Epidemiology,2011,21(4):395-407.
[13] European Food Safety Authority(EFSA).Scientific Opinion on the risks to public health related to the presence of perchlorate in food,in particular fruits and vegetables[J].EFSA Journal,2014,12(10):3869.
[14] Schier J G,Wolkin A F,Valentin-Blasini L,et al.Perchlorate exposure from infant formula and comparisons with the perchlorate reference dose[J].Journal of Exposure Science and Environmental Epidemiology,2010,20(3):281-287.
[15] Evaluations of the Joint FAO/WHO Expert Committee on Food Additives(JECFA).PERCHLORATE[EB/OL].https://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=5885,2011.
[16] Bundesinstitut für Risikobewertung(BfR).Fragen und Antworten zu Perchlorat in Lebensmitteln[EB/OL].https://www.bfr.bund.de/de/fragen_und_antworten_zu_perchlorat_in_lebensmitteln-188220.html,2018-02-15.
[17] Steinmaus C M.Perchlorate in water supplies:sources,exposures,and health effects[J].Current Environmental Health Reports,2016,3(2):136-143.
[18] U.S. Food and Drug Administration(FDA).Survey data on perchlorate in food—2005—2006 and 2008—2012 total diet study results[EB/OL].https://www.fda.gov/food/chemical-contaminants-food/survey-data-perchlorate-food-2005-2006-and-2008-2012-total-diet-study-results,2017-12-27.
[19] Kirk A B,Smit E E,Tian K,et al.Perchlorate in milk[J].Environmental Science & Technology,2003,37(21):4979-4981.
[20] Kirk A B,Martinelango P K,Tian K,et al.Perchlorate and iodide in dairy and breast milk[J].Environmental Science & Technology,2005,39(7):2011-2017.
[21] Dasgupta P K, Kirk R B, Dyke J V,et al.Intake of iodine and perchlorate and excretion in human milk[J].Environmental Science & Technology,2008,42(21):8115-8121.
[22] Sapien J.CDC Study finds rocket fuel chemical in baby formula[EB/OL].SCIENTIFIC AMERICAN:https://www.scientificamerican.com/article/cdc-study-finds-rocket-fuel-chemical-in-baby-formula/#,2009-04-03.
[23] Centers for Disease Control and Prevention(CDC).Perchlorate in Baby Formula Fact Sheet[EB/OL].https://www.cdc.gov/nceh/features/perchlorate_factsheet.htm,2009-04-21.
[24] Arcella D,Binaglia M,Vernazza F.Dietary exposure assessment to perchlorate in the European population[J].EFSA Journal,2017,15(10):e5043.
[25] Hardy A,Benford D,Halldorsson T,et al.Guidance on the risk assessment of substances present in food intended for infants below 16 weeks of age[J].EFSA Journal,2017,15(5):e04849.
[26] Her N,Kim J,Yoon Y.Perchlorate in dairy milk and milk-based powdered infant formula in South Korea[J].Chemosphere(Oxford),2010,81(6):732-737.
[27] 李素颖,侯坤,张卿,等.内蒙古地区婴幼儿配方乳粉中高氯酸盐与氯酸盐膳食暴露风险评估[J].中国食品卫生杂志,2023,35(9):1317-1322.
[28] 黄彬红. 婴幼儿配方奶粉中氯酸盐和高氯酸盐污染情况的调查分析[J].中国乳品工业,2024,52(3):30-35.
[29] 方齐乐,陈宝梁.高氯酸盐污染土壤及地下水的植物-微生物修复研究进展[J].环境科学学报,2011,31(8):1569-1579.
[30] 刘金鑫,肖淑敏,刘思达,等.我国水、大气和土壤环境中高氯酸盐污染现状分析[J].天津城建大学学报,2023,29(6):407-411.
[31] 刘勇建,牟世芬,林爱武,等.北京市饮用水中溴酸盐,卤代乙酸及高氯酸盐研究[J].环境科学,2004,25(2):51-55.
[32] Wu Q,Zhang T,Sun H,et al.Perchlorate in tap water,groundwater,surface waters,and bottled water from China and its association with other inorganic anions and with disinfection byproducts[J].Archives of Environmental Contamination and Toxicology,2010,58(3):543-550.
[33] 康婕,陈鸿剑,李媛,等.婴幼儿配方羊乳粉生产中高氯酸盐污染来源研究[J].中国乳业,2022(9):81-87,94.
[34] Rao B,Estrada N,McGee S,et al.Perchlorate production by photodecomposition of aqueous chlorine solutions[J].Environmental Science & Technology,2012,46(21):11635-11643.
[35] 三国家对食品包装提出新的要求[J].中国包装,2015(4):80.

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婴幼儿配方乳粉高氯酸盐污染风险分析研究

Risk Analysis of Perchlorate Contamination Risk in Infant Formula Milk Powder

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