中国乳业 ›› 2026, Vol. 0 ›› Issue (3): 131-139.doi: 10.12377/1671-4393.26.03.18
吴红军1, 黄学1, 沙娇2, 马浩睿2, 舒琴2, 刘永峰2,*
WU Hongjun1, HUANG Xue1, SHA Jiao2, MA Haorui2, SHU Qin2, LIU Yongfeng2,*
摘要: 本文综述了枸杞与牛奶结合产品的研究现状,系统分析了二者相互作用机制及产品开发应用研究进展。首先,概述了枸杞所含主要生物活性物质及其营养价值,以及牛奶中受枸杞影响的关键营养成分;其次,分析了枸杞-牛奶复合体系在营养互补与功能协同方面的潜力,并评述了相关产品的研究与开发现状。研究表明,该复合产品可显著提升牛奶的营养价值,但其相互作用机理、体内生物利用度及加工过程中活性成分稳定性等关键问题仍待深入探究。本文创新性地提出了枸杞牛奶产品的开发思路,并展望未来应重点围绕加工稳定性、活性保持与作用机制明晰化等方向开展研究,以推动该类功能性乳制品的科学开发与产业化应用。
| [1] Qian D,Ji R F,Gao W,et al.Advances in research on relationships among Lycium species and origin of cultivated Lycium in China[J].Zhongguo Zhongyao Zazhi,2017,42(17):3282-3285. [2] Kulczyński B,Gramza-Michałowska A.Goji Berry(Lycium barbarum):Composition and health effects-a Review[J].Polish Journal of Food and Nutrition Sciences,2016,66(2):67-75. [3] Ma R H,Zhang X X,Ni Z J,et al.Lycium barbarum(Goji)as functional food: a review of its nutrition,phytochemical structure,biological features,and food industry prospects[J].Critical Reviews in Food Science and Nutrition,2023,63(30):10621-10635. [4] 张琦,朱绚绚,熊佳丽,等.枸杞营养功能特性及其产品开发现状[J].食品与发酵工业,2024,50(15):398-408. [5] 兰天,段国珍,祁有朝等.黑果枸杞和黄果枸杞的广泛靶向代谢组学分析[J].食品科学,2024,45(12):52-58. [6] Islam T,Yu X,Badwal T S,et al.Comparative studies on phenolic profiles,antioxidant capacities and carotenoid contents of red goji berry(Lycium barbarum)and black goji berry(Lycium ruthenicum)[J].Chemistry Central Journal,2017,11(1):59. [7] Masci A,Carradori S,Casadei M A,et al.Lycium barbarum polysaccharides: Extraction,purification,structural characterisation and evidence about hypoglycaemic and hypolipidaemic effects. A review[J].Food Chemistry,2018,254):377-389. [8] Vidović B B,Milinčić D D,Marčetić M D,et al.Health benefits and applications of goji berries in functional food products development:A review[J].Antioxidants,2022,11(2):248. [9] 刘冰,马静钰,李婷,等.提取温度对黑果枸杞多糖理化特性及抗氧化、免疫调节活性的影响[J].食品工业科技,2025,46(3):60-70. [10] 松伟,段昊,赵健,等.枸杞原料在缓解视疲劳保健食品中的应用[J].食品科技,2023,48(8):59-64. [11] Miranda M R,Vestuto V,Amodio G,et al.Antitumor mechanisms of lycium barbarum fruit:an overview of in vitro and in vivo potential[J].Life,2024,14(3):420. [12] Wang J,Li S,Zhang H,et al.A review of Lycium barbarum polysaccharides:Extraction,purification,structural-property relationships,and bioactive molecular mechanisms[J].Carbohydrate Research,2024,544:109230. [13] Guo W,Liu S,Khan M Z,et al.Bovine milk microbiota: Key players,origins,and potential contributions to early-life gut development[J].Journal of Advanced Research,2024,59:49-64. [14] 贤歌,刘慧敏,王加启,等.牛奶中A1和A2 β-酪蛋白的结构、功能和检测方法研究进展[J].畜牧兽医学报,2024,55(12):5440-5451. [15] 李明博,刘环宇,张龙舟,等.氨基酸调控牛生长代谢及产品品质的研究进展[J].饲料研究,2021,44(17):137-140. [16] 徐文龙,谢一嘉,潘洋,等.乳制品中美拉德反应有害产物的生成途径、检测方法及其控制策略研究进展[J].食品科学,2025,46(3):274-283. [17] Ma B,Al-Wraikat M,Shu Q,et al.An overview of interactions between goat milk casein and other food components: polysaccharides,polyphenols,and metal ions[J].Foods,2024,13(18):2903. [18] Wang W,Jia R,Hui Y,et al.Utilization of two plant polysaccharides to improve fresh goat milk cheese;Texture,rheological properties,and microstructure characterization[J].Journal of Dairy Science,2023,106(6):3900-3917. [19] Chen L,Li Z Y,He Q,et al.Effect of lotus(Nelumbo nucifera)petals extract on the quality of yogurt and its action mechanism[J].Journal of Food Processing and Preservation,2021,45(5):1-10. [20] Chen L,Chen N,He Q,et al.Effects of different phenolic compounds on the interfacial behaviour of casein and the action mechanism[J].Food Research International,2022,162(Pt B):112110. [21] Wang H,Ke L,Ding Y,et al.Effect of calcium ions on rheological properties and structure of Lycium barbarum L. polysaccharide and its gelation mechanism[J].Food Hydrocolloids,2022,122:107079. [22] Zhang L,Hu Z,Jin X.Analysis of polysaccharides characteristic,monosaccharide composition and xylitol content of Lycium barbarum[J].Chinese Journal of Food Hygiene,2022,34(4):657-662. [23] 张雅莉,黄晓旭,蔡美琴.枸杞多糖的抗氧化及缓解体力疲劳作用研究进展[J].上海交通大学学报(医学版),2015,35(6):911-914,923. [24] Zeng W,Chen L,Li Y,et al.The effect of in vitro digestion on the chemical and antioxidant properties of Lycium barbarum polysaccharides[J].Food Hydrocolloids,2023,139:108507. [25] Wang H,Wang N,Ma L,et al.Polysaccharides from different cultivars of wolfberry:Physicochemical characteristics and protection against oxidative stress[J].Industrial Crops and Products,2023,197:116548. [26] 唐开锋,王剑虹,余家奇枸杞多糖在AP小鼠体内抗炎、抗氧化应激的作用机制[J].中国老年学杂志,2020,40(21):4653-4656. [27] Deng X,Li X,Luo S,et al.Antitumor activity of Lycium barbarum polysaccharides with different molecular weights: an in vitro and in vivo study[J].Food & Nutrition Research,2017,61(1):1399770. [28] Zhou W,Yang T,Xu W,et al.The polysaccharides from the fruits of Lycium barbarum L. confer anti-diabetic effect by regulating gut microbiota and intestinal barrier[J].Carbohydrate Polymers,2022,291:119626. [29] 牛忻,袁继承,吴北霞.枸杞多糖研究进展[J].食品安全导刊,2024,9:151-160. [30] Fratianni A,Niro S,Alam M D R,et al.Effect of a physical pre-treatment and drying on carotenoids of goji berries(Lycium barbarum L.)[J].Food Science & Technology,2018,92:318-323. [31] Zhang C,Li B.Fabrication of nanoemulsion delivery system with high bioaccessibility of carotenoids from Lycium barbarum by spontaneous emulsification[J].Food Science & Nutrition,2022,10(8):2582-2589. [32] Wang C,Ma C,Gong L,et al.Preventive and therapeutic role of betaine in liver disease:A review on molecular mechanisms[J].European Journal of Pharmacology,2021(912):174604. [33] Yang R,Hu J,Ding J,et al.Ultrasound assisted fabrication of the yeast protein-chitooligosaccharide-betanin composite for stabilization of betanin[J].Ultrasonics Sonochemistry,2024,104:106823. [34] Yong H,Liu J.Recent advances in the preparation,physical and functional properties,and applications of anthocyanins-based active and intelligent packaging films[J].Food Packaging and Shelf Life,2020,26:100550. [35] Liu B,Gao J,Liu X,et al.Preparation of soybean isolate protein/xanthan gum/agar-Lycium ruthenicum anthocyanins intelligent indicator films and its application in mutton preservation[J].International Journal of Biological Macromolecules,2024,283(Pt 3):137751. [36] De Groot A,Bijl E,Sagis L M C.Casein network formation at oil-water interfaces is reduced by β-casein and increased by Ca2+[J].Food Hydrocolloids,2025,160(Pt 1):110741. [37] Liu Z,Gao X,Ruan H,et al.Determination of αs1-Casein and αs2-Casein in hypoallergenic infant formula by extended specific peptide -isotope-labeled internal standard dilution-LC-MS/MS[J].Food Bioscience,2024,62:105197. [38] Shori A B,Ling Y H,Baba A S.Effects of Lycium barbarum and fish collagen in cheese on the proteolytic degradation profile with anti‐ACE activity[J].Journal of Food Processing and Preservation,2021,45(3):e15239. [39] Zeng X,Wang Y,Yang S,et al.The functionalities and applications of whey/whey protein in fermented foods: a review[J]. Food Science and Biotechnology,2024,33(4):769-790. [40] Guo X,Guo X,Meng H,et al.Influences of different pectins on the emulsifying performance of conjugates formed between pectin and whey protein isolate[J].International Journal of Biological Macromolecules,2019,123:246-254. [41] Zhang G,Li Y,Song T,et al.Improvement in emulsifying properties of whey protein-Rhamnolipid conjugates through short-time heat treatment[J].Colloids and Surfaces B:Biointerfaces,2019,181:688-695. [42] Shen X,Zhao C,Guo M.Effects of high intensity ultrasound on acid-induced gelation properties of whey protein gel[J].Ultrasonics Sonochemistry,2017,39:810-815. [43] 张思雨,程建军,孙玉雪,等.热处理对乳清蛋白原料起泡性、理化特性的影响及关系研究[J].食品与发酵工业,2023,49(22):117-124. [44] Tian L,Zhang S,Yi J,et al.Formation of antioxidant multilayered coatings for the prevention of lipid and protein oxidation in oil-in-water emulsions: Lycium barbarum polysaccharides and whey proteins[J].Journal of Agricultural and Food Chemistry,2021,69(51):15691-15698. [45] Wang H,Zhang J,Rao P,et al.Mechanistic insights into the interaction of Lycium barbarum polysaccharide with whey protein isolate: Functional and structural characterization[J].Food Chemistry, 2024,463(Pt 1):141080. [46] Al-Wraikat M,Zhang L,Li L,et al.Recent advances in wolfberry polysaccharides and whey protein-based biopolymers for regulating the diversity of gut microbiota and its mechanism:A review[J].International Journal of Biological Macromolecules,2024,281(Pt 3):136401. [47] Li A,Zheng J,Han X,et al.Advances in low-lactose/lactose-free dairy products and their production[J].Foods,2023,12(13):2553. [48] Wang H,Zhang J,Rao P,et al.Mechanistic insights into the interaction of Lycium barbarum polysaccharide with whey protein isolate: Functional and structural characterization[J].Food Chemistry,2025,463(Pt 1):141080. [49] 成堃,袁雪娇,高星,等.响应面法优化金银花枸杞风味酸奶的发酵工艺[J].中国酿造,2020,39(2):206-210. [50] 齐瑾,郭帅,陈彦辉,等.枸杞益生菌酸奶特性评价及其多酚类化合物的代谢变化[J].食品工业科技,2025,46(10):163. [51] Xing H,Liu X,Hu Y,et al.Effect of Lycium barbarum polysaccharides on heat-induced gelation of soy protein isolate[J].Food Hydrocolloids,2024(147):109323. [52] He Z,Ma T,Zhang W,et al.Heat-induced gel formation by whey protein isolate-Lycium barbarum polysaccharides at varying pHs[J].Food Hydrocolloids,2021(115):106607. [53] Sun H,Ge W,Song D,et al.Structure,physicochemical and adsorption properties of insoluble dietary fiber from Lycium barbarum residue: A potential functional factor[J].Food Bioscience,2024(61):104703. [54] 胡欣欣. 枸杞膳食纤维的制备表征、功能活性及应用研究[D].杭州:浙江大学,2023. [55] Wang W,Jia R,Hui Y,et al.Utilization of two plant polysaccharides to improve fresh goat milk cheese:Texture,rheological properties,and microstructure characterization[J].Journal of Dairy Science,2023,106(6):3900-3917. [56] Chang R,Liu J,Ji F,et al.Hypoglycemic effect of recrystallized resistant starch on high-fat diet-and streptozotocin-induced type 2 diabetic mice via gut microbiota modulation[J].International Journal of Biological Macromolecules,2024,261(Pt 2):129812. [57] Vidana Gamage G C,Goh J K,Choo W S.Application of anthocyanins from black goji berry in fermented dairy model food systems:An alternate natural purple color[J].Food Science & Technology,2024(198):115975. [58] 胡永芯,谭宏凯,胡巍,等牛乳乳清中主要过敏原的B细胞表位定位[J].食品科学,2022,43(20):148-156. [59] Perusko M,Roest M,Stanic‐Vucinic D,et al.Glycation of the major milk allergen β‐lactoglobulin changes its allergenicity by alterations in cellular uptake and degradation[J].Molecular Nutrition & Food Research,2018,62(17):1800341. |
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